Interaction Information Along Lifespan of the Resting Brain Dynamics Reveals a Major Redundant Role of the Default Mode Network

被引：16

作者：

Camino-Pontes, Borja ^{[1
]}

Diez, Ibai ^{[2
,3
,4
]}

Jimenez-Marin, Antonio ^{[1
]}

Rasero, Javier ^{[1
]}

Erramuzpe, Asier ^{[1
,11
]}

Bonifazi, Paolo ^{[1
,5
]}

Stramaglia, Sebastiano ^{[6
,7
]}

Swinnen, Stephan ^{[8
,9
]}

Cortes, Jesus M. ^{[1
,5
,10
]}

机构：

[1] Biocruces Hlth Res Inst, Computat Neuroimaging Lab, Baracaldo 48903, Spain

[2] Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Funct Neurol Res Grp, Boston, MA 02115 USA

[3] Harvard Med Sch, Massachusetts Gen Hosp, Dept Nucl Med, Gordon Ctr, Boston, MA 02115 USA

[4] Tecnalia Hlth Dept, Neurotechnol Lab, Derio 48160, Spain

[5] Ikerbasque, Basque Fdn Sci, Bilbao 48013, Spain

[6] Univ Bari, Dipartimento Interateneo Fis, I-70126 Bari, Italy

[7] INFN, I-70126 Bari, Italy

[8] Katholieke Univ Leuven, Dept Movement Sci, Movement Control & Neuroplast Res Grp, B-3001 Leuven, Belgium

[9] Katholieke Univ Leuven, LBI, B-3000 Leuven, Belgium

[10] Univ Basque Country, Dept Cell Biol & Histol, Leioa 48940, Spain

[11] Hebrew Univ Jerusalem, Edmond & Lily Safra Ctr Brain Sci, IL-9190401 Jerusalem, Israel

来源：

ENTROPY | 2018年 / 20卷 / 10期

关键词：

interaction information; synergy; redundancy; default mode network; resting state; lifespan; MILD COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; FUNCTIONAL CONNECTIVITY; STATE NETWORKS; STRUCTURAL CONNECTIVITY; NEUROIMAGING DATA; FMRI; IDENTIFICATION; CONSCIOUSNESS; SCHIZOPHRENIA;

D O I：

10.3390/e20100742

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Interaction Information (II) generalizes the univariate Shannon entropy to triplets of variables, allowing the detection of redundant (R) or synergetic (S) interactions in dynamical networks. Here, we calculated II from functional magnetic resonance imaging data and asked whether R or S vary across brain regions and along lifespan. Preserved along lifespan, we found high overlapping between the pattern of high R and the default mode network, whereas high values of S were overlapping with different cognitive domains, such as spatial and temporal memory, emotion processing and motor skills. Moreover, we have found a robust balance between R and S among different age intervals, indicating informational compensatory mechanisms in brain networks.

引用

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