An efficient copper-catalyzed formation of highly substituted pyrazoles using molecular oxygen as the oxidant

被引：83

作者：

Suri, Mamta ^{[1
]}

Jousseaume, Thierry ^{[1
]}

Neumann, Julia J. ^{[1
]}

Glorius, Frank ^{[1
]}

机构：

[1] Univ Munster, NRW Grad Sch Chem, Inst Organ Chem, D-48149 Munster, Germany

来源：

GREEN CHEMISTRY | 2012年 / 14卷 / 08期

基金：

欧洲研究理事会;

关键词：

N BOND-FORMATION; C-H ACTIVATION; ARYL KETONES; DERIVATIVES; NITRILES; ANILINES; INDOLES; ENAMINONES; INHIBITORS; ARYLATION;

D O I：

10.1039/c2gc35476d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient Cu-catalyzed formation of tetra-substituted pyrazoles is reported. In this atom economic process, readily available enamines and nitriles are reacted by C-C and N-N bond formation. Oxygen has been successfully used as the oxidant, which has important economic and environmental advantages. A broad scope of enamines and nitriles can be utilized in this process.

引用

页码：2193 / 2196

页数：4

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