Polymorphisms in the ATG16L1 Gene are Associated with Psoriasis Vulgaris

被引：61

作者：

Douroudis, Konstantinos ^{[1
,2
]}

Kingo, Kuelli ^{[2
,3
]}

Traks, Tanel ^{[1
,2
]}

Reimann, Ene ^{[1
,2
]}

Raud, Kristi ^{[1
,2
]}

Raetsep, Ranno ^{[1
,2
]}

Moessner, Rotraut ^{[4
]}

Silm, Helgi ^{[2
,3
]}

Vasar, Eero ^{[1
,2
]}

Koks, Sulev ^{[1
,2
]}

机构：

[1] Univ Tartu, Dept Physiol, EE-50090 Tartu, Estonia

[2] Univ Tartu, Ctr Translat Med, EE-50090 Tartu, Estonia

[3] Univ Tartu, Dept Dermatol & Venereol, EE-50090 Tartu, Estonia

[4] Univ Gottingen, Dept Dermatol, Gottingen, Germany

来源：

ACTA DERMATO-VENEREOLOGICA | 2012年 / 92卷 / 01期

关键词：

GENOME-WIDE ASSOCIATION; AUTOPHAGY; PROTEIN; DISEASE; MOUSE; LOCI;

D O I：

10.2340/00015555-1183

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：85 / 87

页数：3

共 15 条

[1] A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells [J].

Cadwell, Ken ;

Liu, John Y. ;

Brown, Sarah L. ;

Miyoshi, Hiroyuki ;

Loh, Joy ;

Lennerz, Jochen K. ;

Kishi, Chieko ;

Kc, Wumesh ;

Carrero, Javier A. ;

Hunt, Steven ;

Stone, Christian D. ;

Brunt, Elizabeth M. ;

Xavier, Ramnik J. ;

Sleckman, Barry P. ;

Li, Ellen ;

Mizushima, Noboru ;

Stappenbeck, Thaddeus S. ;

Virgin, Herbert W. .

NATURE, 2008, 456 (7219) :259-U62

[2] The clinical genetics of psoriasis [J].

Campalani, E ;

Barker, JNWN .

CURRENT GENOMICS, 2005, 6 (01) :51-60

[3] NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation [J].

Cooney, Rachel ;

Baker, John ;

Brain, Oliver ;

Danis, Benedicte ;

Pichulik, Tica ;

Allan, Philip ;

Ferguson, David J. P. ;

Campbell, Barry J. ;

Jewell, Derek ;

Simmons, Alison .

NATURE MEDICINE, 2010, 16 (01) :90-U128

[4] The CD226 Gly307Ser gene polymorphism is associated with severity of psoriasis [J].

Douroudis, Konstantinos ;

Kingo, Kuelli ;

Silm, Helgi ;

Reimann, Ene ;

Traks, Tanel ;

Vasar, Eero ;

Koks, Sulev .

JOURNAL OF DERMATOLOGICAL SCIENCE, 2010, 58 (02) :160-161

[5] A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 [J].

Hampe, Jochen ;

Franke, Andre ;

Rosenstiel, Philip ;

Till, Andreas ;

Teuber, Markus ;

Huse, Klaus ;

Albrecht, Mario ;

Mayr, Gabriele ;

De La Vega, Francisco M. ;

Briggs, Jason ;

Guenther, Simone ;

Prescott, Natalie J. ;

Onnie, Clive M. ;

Haesler, Robert ;

Sipos, Bence ;

Foelsch, Ulrich R. ;

Lengauer, Thomas ;

Platzer, Matthias ;

Mathew, Christopher G. ;

Krawczak, Michael ;

Schreiber, Stefan .

NATURE GENETICS, 2007, 39 (02) :207-211

[6] Autophagy Suppresses Tumorigenesis through Elimination of p62 [J].

Mathew, Robin ;

Karp, Cristina M. ;

Beaudoin, Brian ;

Vuong, Nhan ;

Chen, Guanghua ;

Chen, Hsin-Yi ;

Bray, Kevin ;

Reddy, Anupama ;

Bhanot, Gyan ;

Gelinas, Celine ;

DiPaola, Robert S. ;

Karantza-Wadsworth, Vassiliki ;

White, Eileen .

CELL, 2009, 137 (06) :1062-1075

[7] Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate [J].

Mizushima, N ;

Kuma, A ;

Kobayashi, Y ;

Yamamoto, A ;

Matsubae, M ;

Takao, T ;

Natsume, T ;

Ohsumi, Y ;

Yoshimori, T .

JOURNAL OF CELL SCIENCE, 2003, 116 (09) :1679-1688

[8] Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production [J].

Saitoh, Tatsuya ;

Fujita, Naonobu ;

Jang, Myoung Ho ;

Uematsu, Satoshi ;

Yang, Bo-Gie ;

Satoh, Takashi ;

Omori, Hiroko ;

Noda, Takeshi ;

Yamamoto, Naoki ;

Komatsu, Masaaki ;

Tanaka, Keiji ;

Kawai, Taro ;

Tsujimura, Tohru ;

Takeuchi, Osamu ;

Yoshimori, Tamotsu ;

Akira, Shizuo .

NATURE, 2008, 456 (7219) :264-U68

[9] A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 [J].

Strange, Amy ;

Capon, Francesca ;

Spencer, Chris C. A. ;

Knight, Jo ;

Weale, Michael E. ;

Allen, Michael H. ;

Barton, Anne ;

Band, Gavin ;

Bellenguez, Celine ;

Bergboer, Judith G. M. ;

Blackwell, Jenefer M. ;

Bramon, Elvira ;

Bumpstead, Suzannah J. ;

Casas, Juan P. ;

Cork, Michael J. ;

Corvin, Aiden ;

Deloukas, Panos ;

Dilthey, Alexander ;

Duncanson, Audrey ;

Edkins, Sarah ;

Estivill, Xavier ;

Fitzgerald, Oliver ;

Freeman, Colin ;

Giardina, Emiliano ;

Gray, Emma ;

Hofer, Angelika ;

Hueffmeier, Ulrike ;

Hunt, Sarah E. ;

Irvine, Alan D. ;

Jankowski, Janusz ;

Kirby, Brian ;

Langford, Cordelia ;

Lascorz, Jesus ;

Leman, Joyce ;

Leslie, Stephen ;

Mallbris, Lotus ;

Markus, Hugh S. ;

Mathew, Christopher G. ;

McLean, W. H. Irwin ;

McManus, Ross ;

Moessner, Rotraut ;

Moutsianas, Loukas ;

Naluai, Asa T. ;

Nestle, Frank O. ;

Novelli, Giuseppe ;

Onoufriadis, Alexandros ;

Palmer, Colin N. A. ;

Perricone, Carlo ;

Pirinen, Matti ;

Plomin, Robert .

NATURE GENETICS, 2010, 42 (11) :985-U106

[10] Genome-wide association analysis identifies three psoriasis susceptibility loci [J].

Stuart, Philip E. ;

Nair, Rajan P. ;

Ellinghaus, Eva ;

Ding, Jun ;

Tejasvi, Trilokraj ;

Gudjonsson, Johann E. ;

Li, Yun ;

Weidinger, Stephan ;

Eberlein, Bernadette ;

Gieger, Christian ;

Wichmann, H. Erich ;

Kunz, Manfred ;

Ike, Robert ;

Krueger, Gerald G. ;

Bowcock, Anne M. ;

Mrowietz, Ulrich ;

Lim, Henry W. ;

Voorhees, John J. ;

Abecasis, Goncalo R. ;

Weichenthal, Michael ;

Franke, Andre ;

Rahman, Proton ;

Gladman, Dafna D. ;

Elder, James T. .

NATURE GENETICS, 2010, 42 (11) :1000-U125

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