Autologous peripheral blood stem cell transplantation for POEMS syndrome (Reprinted)

被引：89

作者：

Kuwabara, S

Misawa, S

Kanai, K

Kikkawa, Y

Nishimura, M

Nakaseko, C

Cho, RK

Hattori, T

机构：

[1] Chiba Univ, Sch Med, Dept Neurol, Chiba 2608670, Japan

[2] Chiba Univ, Sch Med, Dept Hematol, Chiba 2608670, Japan

来源：

NEUROLOGY | 2006年 / 66卷 / 01期

关键词：

D O I：

10.1212/01.wnl.0000188757.38495.23

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6 months, symptoms associated with rapid normalization of serum VEGF levels improved.

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页码：105 / 107

页数：3

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