Organosilanes in the synthesis of saturated heterocycles

被引：2

作者：

Diez-Poza, Carlos ^{[1
]}

Fernandez-Pena, Laura ^{[1
]}

Cherubin, Alberto ^{[1
]}

Lion-Villar, Juan ^{[1
]}

Barbero, Asuncion ^{[1
]}

机构：

[1] Fac Sci, Dept Organ Chem, Campus Miguel Delibes, Valladolid 47011, Spain

来源：

ARKIVOC | 2020年

关键词：

Heterocycles; silyl-Prins reaction; cyclization; organosilanes; stereoselection; domino processes; ACID-CATALYZED CYCLIZATION; SILYL-PRINS CYCLIZATION; STEREOSELECTIVE-SYNTHESIS; VINYLSILANES BEARING; ASYMMETRIC-SYNTHESIS; CYCLIC ETHERS; TRIFLIC ACID; ALLENE; HYDROALKOXYLATION; TETRAHYDROFURANS;

D O I：

10.24820/ark.5550190.p011.111

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This account summarizes the studies towards the synthesis of saturated heterocycles using the chemistry of organosilanes. Two different synthetic approaches are described: a) the acid-mediated cyclization of unsaturated silyl alcohols and b) the silyl-Prins (or silyl-aza-Prins) cyclization of silylated alkenols. The effect of substitution on the selectivity of the annulation process is evaluated. [GRAPHICS] .

引用

页码：96 / 116

页数：21

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