Extracting atomic numbers and electron densities from a dual source dual energy CT scanner: Experiments and a simulation model

被引:80
作者
Landry, Guillaume
Reniers, Brigitte
Granton, Patrick Vincent
van Rooijen, Bart [2 ]
Beaulieu, Luc [3 ,4 ,5 ]
Wildberger, Joachim E. [2 ]
Verhaegen, Frank [1 ,6 ]
机构
[1] MUMC, GROW Sch Oncol & Dev Biol, Dept Radiat Oncol MAASTRO, NL-6201 Maastricht, BN, Netherlands
[2] MUMC, Dept Radiol, NL-6201 Maastricht, BN, Netherlands
[3] Dept Phys Genie Phys & Opt, Quebec City, PQ, Canada
[4] Univ Laval, Dept Radiooncol, Quebec City, PQ, Canada
[5] Univ Laval, Ctr Rech Cancerol, Quebec City, PQ, Canada
[6] McGill Univ, Dept Oncol, Montreal, PQ, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Dual energy; Computed tomography; Monte Carlo; Atomic number; Dose calculation; CARLO DOSE CALCULATIONS; I-125 PROSTATE IMPLANTS; STOPPING POWER RATIOS; X-RAY TARGETS; TISSUE SEGMENTATION; COMPUTED-TOMOGRAPHY; BRACHYTHERAPY; FILTRATION; DOSIMETRY; SPECTRA;
D O I
10.1016/j.radonc.2011.08.029
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background and purpose: Dual energy CT (DECT) imaging can provide both the electron density rho(e) and effective atomic number Z(eff), thus facilitating tissue type identification. This paper investigates the accuracy of a dual source DECT scanner by means of measurements and simulations. Previous simulation work suggested improved Monte Carlo dose calculation accuracy when compared to single energy CT for low energy photon brachytherapy, but lacked validation. As such, we aim to validate our DECT simulation model in this work. Materials and methods: A cylindrical phantom containing tissue mimicking inserts was scanned with a second generation dual source scanner (SOMATOM Definition FLASH) to obtain Z(eff) and rho(e). A model of the scanner was designed in ImaSim, a CT simulation program, and was used to simulate the experiment. Results: Accuracy of measured Z(eff) (labelled Z) was found to vary from -10% to 10% from low to high Z tissue substitutes while the accuracy on rho(e) from DECT was about 2.5%. Our simulation reproduced the experiments within +/- 5% for both Z and rho(e). Conclusions: A clinical DECT scanner was able to extract Z and rho(e) of tissue substitutes. Our simulation tool replicates the experiments within a reasonable accuracy. (C) 2011 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 100 (2011) 375-379
引用
收藏
页码:375 / 379
页数:5
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