Summary of the Update Session on Clinical Neurotoxicity Studies

被引：28

作者：

Pinyavat, Teeda ^{[1
]}

Warner, David O. ^{[3
]}

Flick, Randall P. ^{[3
,4
]}

McCann, Mary Ellen ^{[5
]}

Andropoulos, Dean B. ^{[6
,7
]}

Hu, Danquig ^{[3
]}

Sall, Jeffrey W. ^{[8
]}

Spann, Marisa N. ^{[2
]}

Ing, Caleb ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Anesthesiol, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA

[3] Mayo Clin, Coll Med, Dept Anesthesiol, Rochester, MN USA

[4] Mayo Clin, Coll Med, Dept Pediat, Rochester, MN USA

[5] Harvard Med Sch, Dept Anesthesiol, Boston, MA USA

[6] Baylor Coll Med, Dept Anesthesiol, Houston, TX 77030 USA

[7] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA

[8] Univ Calif San Francisco, Sch Med, Dept Anesthesiol & Perioperat Care, San Francisco, CA USA

来源：

JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY | 2016年 / 28卷 / 04期

关键词：

anesthesia; pediatric; behavior; cognition; neurodevelopment; clinical research; RANDOMIZED-CONTROLLED-TRIAL; GENERAL-ANESTHESIA; EARLY EXPOSURE; REGIONAL ANESTHESIA; CHILDREN; DEXMEDETOMIDINE; MULTICENTER; PERFORMANCE; PROPOFOL; OUTCOMES;

D O I：

10.1097/ANA.0000000000000347

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

During the Fifth Pediatric Anesthesia Neurodevelopmental Assessment Symposium, experts and stakeholders met to present and discuss recent advances made in the study of neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children. This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered.

引用

页码：356 / 360

页数：5

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