Statins (HMG-CoA reductase inhibitors), cholesterol and stroke

被引：1

作者：

Marta-Moreno, J ^{[1
]}

Echeandia, C ^{[1
]}

Oliveros-Cid, A ^{[1
]}

Figuerola, A ^{[1
]}

Mola, S ^{[1
]}

机构：

[1] Hosp Miguel Servet, Serv Neurol, E-50009 Zaragoza, Spain

来源：

REVISTA DE NEUROLOGIA | 1998年 / 27卷 / 159期

关键词：

cerebral ischemia; cholesterol; HMG-CoA reductase; stroke;

D O I：

10.33588/rn.27159.98262

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The HMG-CoA reductase inhibitors (known as statins) have been shown to reduce morbi-mortality of vascular origin, including transitory ischemic accidents and cerebral infarcts, in a large group of patients. The implications, both clinical and of costs, oblige us to consider analysis of the existing evidence and the answers to a number of questions arising in a field which has not yet received much attention from neurologists.

引用

页码：827 / 830

页数：4

共 50 条

[41] HMG-CoA reductase inhibitors reduce adhesion of human monocytes to endothelial cells
Teupser, D
Bruegel, M
Stein, O
Stein, Y
Thiery, J
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 289 (04) : 838 - 844
[42] Monotherapy with HMG-CoA reductase inhibitors and secondary prevention in coronary artery disease
Rackley, CE
CLINICAL CARDIOLOGY, 1996, 19 (09) : 683 - 689
[43] A QM/MM Evaluation of the Missing Step in the Reduction Mechanism of HMG-CoA by Human HMG-CoA Reductase
Mihaljevic-Juric, Paula
Sousa, Sergio F.
PROCESSES, 2021, 9 (07)
[44] Advantages of lipid-lowering therapy in cerebral ischemia:: Role of HMG-CoA reductase inhibitors
Gil-Núñez, AC
Villanueva, JA
CEREBROVASCULAR DISEASES, 2001, 11 : 85 - 95
[45] Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors
Kiener, PA
Davis, PM
Murray, JL
Youssef, S
Rankin, BM
Kowala, MK
INTERNATIONAL IMMUNOPHARMACOLOGY, 2001, 1 (01) : 105 - 118
[46] Synthesis and Biological Evaluation of Atorvastatin Derivatives as Novel HMG-CoA Reductase Inhibitors
Tong, Jiayi
Wang, Naxin
Xiao, Hua
LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 10 (09) : 817 - 822
[47] Regulation of HMG-CoA synthase and HMG-CoA reductase by insulin and epidermal growth factor in HaCaT keratinocytes
Harris, IR
Höppner, H
Siefken, W
Farrell, AM
Wittern, KP
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2000, 114 (01) : 83 - 87
[48] Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters
Cho, Il Jin
Ahn, Ji Yun
Kim, Suna
Choi, Myung Sook
Ha, Tae Youl
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 367 (01) : 190 - 194
[49] Determination of the Inhibitory Capacity on HMG-CoA Reductase Enzyme by Statins Using Molecular Docking Method
Florescu, Cristina
Rotaru, Luciana Teodora
Varut, Renata Maria
Grigorasi, Gabriela
Kostici, Roxana
Ciobanu, Daniela
Cimpoesu, Diana
REVISTA DE CHIMIE, 2018, 69 (04): : 837 - 839
[50] Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol
Li, Xing-Zi
Jiang, Shi-You
Li, Guo-Qiang
Jiang, Qian-Ru
Li, Jue-Wan
Li, Chen-Chen
Han, Yu-Qin
Song, Bao-Liang
Ma, Xin-Ran
Qi, Wei
Qiu, Wen-Wei
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 236

← 1 2 3 4 5 →