Downregulation of XIAP expression induces apoptosis and sensitizes a panel of pediatric tumor cells to cytotoxic agents

被引：0
|
作者：
Holt, Sarah V. [1 ]
Brookes, Karen E. [1 ]
Durkin, Jon [2 ]
Dive, Caroline [1 ]
Makini, Guy W. J. [1 ]
机构：
[1] Paterson Inst Canc Res, Manchester, Lancs, England
[2] Aegera Therapeut Inc, Quebec City, PQ, Canada
来源：
MOLECULAR CANCER THERAPEUTICS | 2007年 / 6卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：3440S / 3441S
页数：2
相关论文
共 50 条
  • [41] Fluchloralin is cytotoxic and genotoxic and induces apoptosis in mammalian cells
    Sinha, S
    Panneerselvam, N
    Shanmugam, G
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 1998, 31 (03) : 257 - 262
  • [42] Tumor necrosis factor related apoptosis-inducing ligand induces apoptosis and sensitizes resistant hepatic cancer cells to chemotherapy
    何松青
    陈孝平
    张万广
    王海平
    王其
    中华肝脏病杂志, 2004, (08) : 20 - 23
  • [43] Expression of Daxx sensitizes Jurkat T-cells to the apoptosis-inducing effect of chemotherapeutic agents
    Boehrer, S
    Nowak, D
    Kukoc-Zivojnov, N
    Hochmuth, S
    Kim, SZ
    Hoelzer, D
    Mitrou, PS
    Weidmann, E
    Chow, KU
    PHARMACOLOGICAL RESEARCH, 2005, 51 (04) : 367 - 374
  • [44] Sterigmatocystin induces autophagic and apoptotic cell death of liver cancer cells via downregulation of XIAP
    Chen, Xu
    Che, Zhengping
    Wu, Jiajia
    Zeng, Cheng
    Yang, Xiao-long
    Zhang, Lin
    Lin, Zhenghong
    HELIYON, 2024, 10 (08)
  • [45] A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
    Olie, RA
    Simoes-Wüst, AP
    Baumann, B
    Leech, SH
    Fabbro, D
    Stahel, RA
    Zangemeister-Wittke, U
    CANCER RESEARCH, 2000, 60 (11) : 2805 - 2809
  • [46] Small-molecule XIAP antagonist induces apoptosis of leukemia cells.
    Schimmer, AD
    Welsh, K
    Pinilla, C
    Bonneau, M
    Ostresh, J
    Houghten, R
    Nefzi, A
    Reed, JC
    BLOOD, 2002, 100 (11) : 138A - 138A
  • [47] Erratum: Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice
    U Naumann
    O Bähr
    H Wolburg
    S Altenberend
    W Wick
    P Liston
    A Ashkenazi
    M Weller
    Gene Therapy, 2007, 14 : 1434 - 1437
  • [48] Hellebrigenin induces oral cancer cell apoptosis by modulating MAPK signalling and XIAP expression
    Hsieh, Ming-Ju
    Lin, Chia-Chieh
    Lo, Yu-Sheng
    Ho, Hsin-Yu
    Chuang, Yi-Ching
    Chen, Mu-Kuan
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2024, 28 (02)
  • [49] Survivin downregulation by siRNA sensitizes human hepatoma cells to TRAIL-induced apoptosis
    Nakao, Kazuhiko
    Hamasaki, Keisuke
    Ichikawa, Tatsuki
    Arima, Kazuhiko
    Eguchi, Katsumi
    Ishii, Nobuko
    ONCOLOGY REPORTS, 2006, 16 (02) : 389 - 392
  • [50] Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    M Chawla-Sarkar
    S I Bae
    F J Reu
    B S Jacobs
    D J Lindner
    E C Borden
    Cell Death & Differentiation, 2004, 11 : 915 - 923
12345