DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

被引:68
作者
Harris, RS
Sheehy, AM
Craig, HM
Malim, MH
Neuberger, MS
机构
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
[2] Kings Coll London, Guys Kings & St Thomas Sch Med, Dept Infect Dis, London SE1 9RT, England
关键词
D O I
10.1038/ni0703-641
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
New insights into APOBEC editing functions suggest this family of enzymes might protect against invasive attack by foreign DNA.
引用
收藏
页码:641 / 643
页数:3
相关论文
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