How to manage adult coeliac disease: perspective from the NHS England Rare Diseases Collaborative Network for Non-Responsive and Refractory Coeliac Disease

被引：23

作者：

Baggus, Elisabeth Megan Rose ^{[1
]}

Hadjivassiliou, Marios ^{[1
]}

Cross, Simon ^{[1
]}

Penny, Hugo ^{[1
]}

Urwin, Heidi ^{[2
]}

Watson, Sarah ^{[3
]}

Woodward, Jeremy Mark ^{[4
]}

Sanders, David S. ^{[5
]}

机构：

[1] Royal Hallamshire Hosp, Acad Unit Gastroenterol, Sheffield S10 2JF, S Yorkshire, England

[2] Coeliac UK, High Wycombe, Bucks, England

[3] NHS England, Highly Specialised Serv, London, England

[4] Cambridge Intestinal Failure & Transplant, Dept Gastroenterol, Cambridge, England

[5] Royal Hallamshire Hosp, Gastroenterol & Liver Unit, Sheffield, S Yorkshire, England

来源：

FRONTLINE GASTROENTEROLOGY | 2020年 / 11卷 / 03期

关键词：

coeliac disease; small bowel; small bowel disease; small intestine; GLUTEN-FREE DIET; STEM-CELL TRANSPLANTATION; TERM-FOLLOW-UP; INTRAEPITHELIAL LYMPHOCYTES; CLINICAL-FEATURES; MUCOSAL RECOVERY; ELEMENTAL DIET; DIAGNOSIS; MORTALITY; PREVALENCE;

D O I：

10.1136/flgastro-2019-101191

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Adult coeliac disease (CD) affects approximately 1% of the population. Most patients diagnosed will respond to a gluten-free diet; however, up to 30% may have persisting symptoms. Such patients may have ongoing issues associated with adherence, non-responsive CD or refractory CD. This article provides a clinical overview of how to manage this group of patients with persisting symptoms, including an investigational algorithm and details of how to contact the National Health Service England Rare Diseases Collaborative Network for Non-Responsive and Refractory Coeliac Disease. We hope this will be a valuable source of contemporary information for all UK gastroenterologists and internationally.

引用

页码：235 / 242

页数：8

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