Pulmonary Large Cell Neuroendocrine Carcinoma Associated With Lambert-Eaton Syndrome

被引：2

作者：

Hernandez-Arriaga, Pamela ^{[1
]}

Gonzalez-Urquijo, Mauricio ^{[1
]}

Lopez Altamirano, Daniel Fernando ^{[1
]}

Vaca-Cartagena, Bryan ^{[1
]}

Vergil-Vargas, Andres ^{[1
]}

Rios-Pascual, Silviano ^{[1
]}

Perez-Saucedo, Jose Eduardo ^{[1
]}

Sepulveda-Malec, Ricardo ^{[1
]}

机构：

[1] Tecnol Monterrey, Escuela Med & Ciencias Salud, Dr Ignacio Morones Prieto O 3000, Monterrey 64710, Mexico

来源：

CLINICAL PATHOLOGY | 2021年 / 14卷

关键词：

Lambert-Eaton; myasthenic syndrome; large cell neuroendocrine carcinoma; lung cancer; paraneoplastic syndrome; MYASTHENIC SYNDROME;

D O I：

10.1177/2632010X211051741

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Lambert-Eaton syndrome is a rare paraneoplastic disorder of the neuromuscular junction, characterized by impaired release of acetylcholine, which causes proximal muscle weakness, depressed tendon reflexes, and autonomic changes. Most cases of Lambert-Eaton syndrome present in small-cell lung carcinoma, and only a few cases have been reported in other lung subtypes. Herein, we report a case of 69 years old male patient with Lambert-Eaton syndrome as a rare association with a pulmonary large-cell neuroendocrine carcinoma, which presented 5 months before neoplasm diagnosis. A lobectomy was auspiciously performed. A review of the literature is also presented.

引用

页数：4

共 8 条

[1] Neuroendocrine lung tumors and disorders of the neuromuscular junction [J].