Nickel(II) Complexes with Pentane-2,4-dione Bis(4-allylthiosemicarbazone)

被引:1
作者
Gulea, A. P. [1 ]
Graur, V. O. [1 ]
Chumakov, Yu. M. [2 ,3 ]
Petrenko, P. A. [2 ]
Garbuz, O. S. [1 ,4 ]
Tsapkov, V. I. [1 ]
Gudumac, V. S. [5 ]
机构
[1] State Univ Moldova, MD-2009 Kishinev, Moldova
[2] Inst Appl Phys, Kishinev 2008, Moldova
[3] Gebze Inst Technol, TR-41400 Kocaeli, Turkey
[4] Inst Zool, Kishinev 2028, Moldova
[5] State Univ Med & Pharm Nicolae Testemitanu, MD-2004 Kishinev, Moldova
关键词
Ni(II) coordination compounds; acetylacetone bis(4-allylthiosemicarbazone); anticancer activity; IN-VITRO ANTILEUKEMIA; THIOSEMICARBAZONES; ANTIBACTERIAL; ANTIFUNGAL;
D O I
10.1134/S107036322001017X
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Reaction of pentane-2,4-dione with N-(prop-2-en-1-yl)hydrazinecarbothioamide at a 1: 2 molar ratio in ethanol resulted in the formation of a pyrazole derivative. The latter reacted with nickel perchlorate at a 1: 1 molar ratio to form the nickel complex with pentane-2,4-dione bis(4-allylthiosemicarbazone). The same type of nickel complex was obtained as a result of N-(prop-2-en-1-yl)hydrazinecarbothioamide reaction with pentane-2,4-dione and nickel nitrate at a 2: 1: 1 molar ratio. Antimicrobial, antifungal, antioxidant, and anticancer activities of the obtained compounds were studied.
引用
收藏
页码:111 / 117
页数:7
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