Diffractometric Biochemical Sensing with Smart Hydrogels

被引：8

作者：

Chang, Chun-Li ^{[1
,2
]}

Ding, Zhenwen ^{[2
,3
]}

Patchigolla, Venkata N. L. R. ^{[1
,2
]}

Ziaie, Babak ^{[2
,4
]}

Savran, Cagri A. ^{[1
,2
]}

机构：

[1] Purdue Univ, Sch Mech Engn, W Lafayette, IN 47907 USA

[2] Purdue Univ, Birck Nanotechnol Ctr, W Lafayette, IN 47907 USA

[3] Purdue Univ, Dept Phys, W Lafayette, IN 47907 USA

[4] Purdue Univ, Sch Elect & Comp Engn, W Lafayette, IN 47907 USA

来源：

2010 IEEE SENSORS | 2010年

关键词：

SENSOR; PH; CANTILEVER;

D O I：

10.1109/ICSENS.2010.5690402

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We report reflective diffraction gratings made from smart hydrogels for ultrasensitive biochemical detection. As an example for a biochemically responsive hydrogel, we chose a pH-sensitive hydrogel to construct diffraction gratings that swell or shrink due to changes in pH. Interferometric analysis of the grating enabled detection of the hydrogel's swelling/shrinking with nanoscale precision with a resolution of 6x10(-4) pH units. The developed system is remarkably simple both to fabricate and operate. Moreover, the concept of the hydrogel grating is generic and can be widely applied to hydrogels responsive to other stimuli.

引用

页码：1617 / 1621

页数：5

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