Genetics of chronic tinnitus

被引：22
作者：
Sand, P. G. [1 ]
Langguth, B. [1 ]
Kleinjung, T. [2 ]
Eichhammer, P. [1 ]
机构：
[1] Univ Regensburg, Dept Psychiat, D-93053 Regensburg, Germany
[2] Univ Regensburg, Dept Otorhinolaryngol, D-93053 Regensburg, Germany
来源：
TINNITUS: PATHOPHYSIOLOGY AND TREATMENT | 2007年 / 166卷
关键词：
tinnitus; genetic risk; endophenotype; biomarker;
D O I：
10.1016/S0079-6123(07)66014-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Susceptibility to chronic tinnitus is highly variable and of particular interest when it comes to defining strategies for prevention and treatment. While several rare monogenic disorders have been described that are associated with tinnitus, the genetic underpinnings of the more common forms of the syndrome are still poorly understood. The present article incorporates recent advancements in the field, including the epidemiology of tinnitus in subjects with neuropsychiatric illness, and highlights pilot studies of candidate genes.
引用
收藏
页码：159 / 168
页数：10
相关论文
共 97 条
[41]  
KENNEDY V, 2006, EFFECT GENENTIC HEAR, P187
[42]  
KESSLER RC, 1994, ARCH GEN PSYCHIAT, V51, P8
[43]  
KLEINJUNG T, 2007, OTOLARYNGOL HEAD NEC, V136
[44]  
KLEINJUNG T, 2006, J OTOLOGY, V2, P83
[45]  
KLEINJUNG T, 2006, OTOLARYNGOL HEAD NEC, V135, pP249
[46]   Psychological factors in Severe Disabling Tinnitus [J].
Langenbach, M .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2005, 131 (09) :829-829
[47]   THERAPEUTIC EFFECTS OF DELTA-SLEEP-INDUCING PEPTIDE (DSIP) IN PATIENTS WITH CHRONIC, PRONOUNCED PAIN EPISODES - A CLINICAL PILOT-STUDY [J].
LARBIG, W ;
GERBER, WD ;
KLUCK, M ;
SCHOENENBERGER, GA .
EUROPEAN NEUROLOGY, 1984, 23 (05) :372-385
[48]  
Lessmann V, 1998, GEN PHARMACOL-VASC S, V31, P667
[49]   First onset versus recurrence of depression: Differential processes of psychosocial risk [J].
Lewinsohn, PM ;
Allen, NB ;
Seeley, JR ;
Gotlib, IH .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1999, 108 (03) :483-489
[50]   Molecular analyses of KCNQ1-5 potassium channel mRNAs in rat and guinea pig inner ears:: expression, cloning, and alternative splicing [J].
Liang, GH ;
Jin, Z ;
Ulfendahl, M ;
Järlebark, L .
ACTA OTO-LARYNGOLOGICA, 2006, 126 (04) :346-352
12345678910