Dynamics of electrocardiographic indices in patients with mild to moderate arterial hypertension during long-term controlled antihypertensive therapy and subsequent long-term follow-up

In 62 patients with stage I - II essential hypertension (hypertensive disease) without severe concomitant diseases long-term controlled antihypertensive therapy led to significant lowering of blood pressure, decreases in frequency of ECG signs of left ventricular and left atrial hypertrophy and ST-T segment changes. Subsequent follow-up for 1 year during which the ambulatory treatment of patients was not controlled revealed a tendency to a rise in frequency of electrocardiographic criteria of left ventricular hypertrophy and significant increase in frequency of registration of voltage signs of hypertrophy compared to data obtained just after termination of the period of controlled therapy. This negative dynamics was more pronounced in patients with higher diastolic blood pressure.