Gold finger formation studied by high-resolution mass spectrometry and in silico methods

被引：32

作者：

Laskay, U. A. ^{[1
]}

Garino, C. ^{[2
,3
]}

Tsybin, Y. O. ^{[1
]}

Salassa, L. ^{[4
,5
,6
]}

Casini, A. ^{[7
]}

机构：

[1] Ecole Polytech Fed Lausanne, Biomol Mass Spectrometry Lab, CH-1015 Lausanne, Switzerland

[2] Univ Turin, Dept Chem, I-10125 Turin, Italy

[3] Univ Turin, NIS Ctr Excellence, I-10125 Turin, Italy

[4] CIC biomaGUNE, Donostia San Sebastia 20009, Spain

[5] Euskal Herriko Unibertsitatea, Kim Fak, Donostia San Sebastian, Euskadi, Spain

[6] Donostia Int Phys Ctr, Donostia San Sebastian, Euskadi, Spain

[7] Univ Groningen, Res Inst Pharm, Dept Pharmacokinet Toxicol & Targeting, NL-9713 AV Groningen, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 09期

关键词：

ZINC-FINGER; FORCE-FIELD; PROTEINS; INHIBITION;

D O I：

10.1039/c4cc07490d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High-resolution mass spectrometry and quantum mechanics/molecular mechanics studies were employed for characterizing the formation of two gold finger (GF) domains from the reaction of zinc fingers (ZF) with gold complexes. The influence of both the gold oxidation state and the ZF coordination sphere in GF formation provided useful insights into the possible design of new gold complexes targeting specific ZF motifs.

引用

页码：1612 / 1615

页数：4

共 50 条

[1] High-resolution mass spectrometry
Maurer, Hans H.
Muddiman, David C.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 403 (05) : 1201 - 1202
[2] High-resolution mass spectrometry
Hans H. Maurer
David C. Muddiman
Analytical and Bioanalytical Chemistry, 2012, 403 : 1201 - 1202
[3] MASS SPECTROMETRY -A SPOTLIGHT ON HIGH-RESOLUTION MASS SPECTROMETRY
Cook, Brandoch
Lab Manager, 2024, 19 (01): : 54 - 55
[4] High-resolution mass spectrometry for bioanalytical applications: Is this the new gold standard?
Kaufmann, Anton
JOURNAL OF MASS SPECTROMETRY, 2020, 55 (09):
[5] Resolution Ladder for High-Resolution Mass Spectrometry
Schittmayer, Matthias
Birner-Gruenberger, Ruth
ANALYTICAL CHEMISTRY, 2017, 89 (18) : 9611 - 9615
[6] High-Resolution Native Mass Spectrometry
Tamara, Sem
den Boer, Maurits A.
Heck, Albert J. R.
CHEMICAL REVIEWS, 2022, 122 (08) : 7269 - 7326
[7] High-resolution mass spectrometry for glycoproteomics
Bo, Siyue
Zhang, Rumeng
Zhao, Lingbo
Yang, Shuang
Lu, Zhaohui
Wang, Perry G.
BIOANALYSIS, 2023, 15 (02) : 57 - 61
[8] Evaluation of plasma peptides extraction methods by high-resolution mass spectrometry
Zakharova, N. V.
Shornikova, A. Y.
Bugrova, A. E.
Baybakova, V. V.
Indeykina, M. I.
Kononikhin, A. S.
Popov, I. A.
Kechko, O. I.
Makarov, A. A.
Nikolaev, E. N.
EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2017, 23 (04) : 209 - 212
[9] High-Resolution Mass Spectrometry based methods to improve the characterization of genotoxicity
Balbo, Silvia
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2023, 64 : 21 - 21
[10] In vitro metabolism of triclosan studied by liquid chromatography–high-resolution tandem mass spectrometry
Amal Guesmi
Lekha Sleno
Analytical and Bioanalytical Chemistry, 2020, 412 : 335 - 342

← 1 2 3 4 5 →