SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME NEW THIAZOLYL-PYRAZOLINES BEARING 1,2,4-TRIAZOLE MOIETY

被引：3
|
作者：
Chen, Sheng-Qin [1 ]
Zhang, Yi-Chao [2 ]
Liu, Fang-Ming [1 ]
机构：
[1] Hangzhou Normal Univ, Coll Mat & Chem Engn, Hangzhou 310036, Zhejiang, Peoples R China
[2] WuXi PharmaTech Co Ltd, Shanghai, Peoples R China
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2011年 / 186卷 / 02期
关键词：
Carbothioamide; pyrazoline; thiazole; 1,2,4-triazole; THERAPEUTIC-USE; DERIVATIVES; ANTIBACTERIAL; PROTEIN;
D O I：
10.1080/10426507.2010.497519
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
In this study, several new 1-(4-aryl-5-triazolyl-2-thiazolyl)-3,5-diaryl-2-pyrazolines (3a-r) were synthesized by reacting 3,5-diaryl1-thiocarbamoyl-2-pyrazolines (1) with 2-bromo-1-aryl-2-(1H-1,2,4-triazol-1-yl) ethanones (2) in boiling ethanol. The chemical structures of the compounds were verified by IR, (1)H NMR, ESI-MS spectroscopic data, and elemental analyses.
引用
收藏
页码：319 / 325
页数：7
相关论文
共 50 条
  • [1] Synthesis and Crystal Structure of New Thiazolyl-Pyrazoline Derivatives Bearing 1,2,4-Triazole Moiety
    Yong-Ming Zeng
    Sheng-Qin Chen
    Fang-Ming Liu
    Journal of Chemical Crystallography, 2012, 42 : 24 - 28
  • [2] Synthesis and Crystal Structure of New Thiazolyl-Pyrazoline Derivatives Bearing 1,2,4-Triazole Moiety
    Zeng, Yong-Ming
    Chen, Sheng-Qin
    Liu, Fang-Ming
    JOURNAL OF CHEMICAL CRYSTALLOGRAPHY, 2012, 42 (01) : 24 - 28
  • [3] Synthesis and Antimicrobial Evaluation of New Schiff Base Hydrazones Bearing 1,2,4-Triazole Moiety
    Popiolek, Lukasz
    Kosikowska, Urszula
    Wujec, Monika
    Malm, Anna
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2014, 189 (11) : 1611 - 1623
  • [4] SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME NOVEL THIAZOLYL-PYRAZOLINE DERIVATIVES CONTAINING 1,2,3-TRIAZOLE MOIETY
    Shi, Hai
    Liu, Fang-Ming
    Shen, Song-Wei
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2011, 186 (02) : 263 - 270
  • [5] Synthesis, antiproliferative and antimicrobial activity of new Mannich bases bearing 1,2,4-triazole moiety
    Popiolek, Lukasz
    Rzymowska, Jolanta
    Kosikowska, Urszula
    Hordyjewska, Anna
    Wujec, Monika
    Malm, Anna
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2014, 29 (06) : 786 - 795
  • [6] SYNTHESIS AND CHARACTERIZATION OF NEW THIAZOLYL 1,3,4-OXADIAZOLE AND 1,2,4-TRIAZOLE DERIVATIVES
    Darekar, Nirmala R.
    Dengale, Sujata G.
    Sasane, Kulbhushan A.
    Patil, Shripad M.
    Akolkar, Hemantkumar N.
    HETEROCYCLIC LETTERS, 2024, 14 (02):
  • [7] Synthesis and pharmacological evaluation of new disulfides linked to 1,2,4-triazole bearing urea moiety
    Tang, Rui
    Zhao, Haichuan
    Zhang, Shuai
    Liu, Xiaojia
    Liu, Jinbiao
    Li, Wei
    Wang, Hongying
    Li, Caiwen
    Chen, Baoquan
    MEDICINAL CHEMISTRY RESEARCH, 2023, 32 (08) : 1736 - 1748
  • [8] Synthesis and biological evaluation of disulfides bearing 1,2,4-triazole moiety as antiproliferative agents
    Wang, Xue-Feng
    Zhang, Shuai
    Li, Bao-Lin
    Zhao, Ji-Jun
    Liu, Yu-Ming
    Zhang, Rui-Lian
    Li, Bo
    Chen, Bao-Quan
    MEDICINAL CHEMISTRY RESEARCH, 2017, 26 (12) : 3367 - 3374
  • [9] Synthesis and Antimicrobial Activities of Some New 1,2,4-Triazole Derivatives
    Bektas, Hakan
    Karaali, Nesrin
    Sahin, Deniz
    Demirbas, Ahmet
    Karaoglu, Senguel Alpay
    Demirbas, Neslihan
    MOLECULES, 2010, 15 (04): : 2427 - 2438
  • [10] Synthesis of Some New 1,2,4-triazole Schiff Bases and their Antibacterial Activity Studies
    Sim, Kooi-Mow
    Hoor, Yin-Haw
    Boo, Xin-Lik
    Teh, Chor-Chin
    Lai, Shih-Nee
    Teh, Chor-Pey
    Teo, Kah-Cheng
    LETTERS IN ORGANIC CHEMISTRY, 2023, 20 (09) : 845 - 852
12345