Quantitative structure-activity/property relationships as related to organotin chemistry

被引：7
作者：
Eng, George [1 ]
机构：
[1] Univ Dist Columbia, Div Sci & Math, Washington, DC 20008 USA
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2017年 / 31卷 / 10期
关键词：
organotin; QSAR; review; COMPARATIVE QSAR; MOSQUITO LARVAE; DAPHNIA-MAGNA; SURFACE-AREAS; TIN-COMPOUNDS; TOXICITY; BACTERIA; CHEMICALS; ALGAE; TRICYCLOHEXYLTIN;
D O I：
10.1002/aoc.3712
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The aim of this review is to examine the current status of quantitative structure-activity/property relationships (QSAR/QSPR) as related to organotin chemistry. QSAR/QSPR are mathematical models that relate some measurable biological activity or physical property in a series of similar compounds to a descriptor or descriptors associated with the molecules. Descriptors used in QSAR/QSPR studies are endless, from traditional parameters to newly developed ones. They range from quantum chemical descriptors to physicochemical parameters while QSAR/QSPR studies range from predicting bio-toxicity of various species to estimating chromatographic parameters. The intent of the review is to provide investigators with the current state of knowledge and trends in this area.
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页数：6
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共 73 条
  • [1] Antitumor structure-activity relationship in bis-stannoxane derivatives from pyridine dicarboxylic and benzoic acids
    Antonio Valcarcel, Jose
    Said Razo-Hernandez, Rodrigo
    Leticia Valdez-Velazquez, Laura
    Villanueva Garcia, Manuel
    Ramos Organillo, Angel Andres
    Vazquez-Vuelvas, Oscar F.
    Garcia Ruiz, Miguel A.
    Gomez-Sandoval, Zeferino
    [J]. INORGANICA CHIMICA ACTA, 2012, 392 : 229 - 235
  • [2] ASCHER K. R. S., 1964, WORLD REV PEST CONTR, V3, P188
  • [3] STRUCTURE ACTIVITY RELATIONSHIPS FOR DIORGANOTINS, CHLORINATED BENZENES AND CHLORINATED ANILINES ESTABLISHED WITH BLUEGILL SUNFISH BF-2 CELLS
    BABICH, H
    BORENFREUND, E
    [J]. FUNDAMENTAL AND APPLIED TOXICOLOGY, 1988, 10 (02): : 295 - 301
  • [4] QSAR APPROACH TO UNDERSTAND THE ANTITUMOR-ACTIVITY OF ORGANOTINS
    BARBIERI, R
    [J]. INORGANICA CHIMICA ACTA, 1992, 191 (02) : 253 - 259
  • [5] Synthesis and characterization of some dibutylbis{5-[(E)-2-(aryl)-1-diazenyl]-2-hydroxybenzoato}tin(IV) compounds.: Toxicity studies of di- and, tri-organotin complexes on the second instar of Aeds aegypti mosquito larvae
    Baul, TSB
    Dhar, S
    Rivarola, E
    Smith, FE
    Butcher, R
    Song, XQ
    McCain, M
    Eng, G
    [J]. APPLIED ORGANOMETALLIC CHEMISTRY, 2003, 17 (05) : 261 - 267
  • [6] An in vitro comparative assessment with a series of new triphenyltin(IV) 2-/4-[(E)-2-(aryl)-1-diazenyl]benzoates endowed with anticancer activities: Structural modifications, analysis of efficacy and cytotoxicity involving human tumor cell lines
    Baul, Tushar S. Basu
    Paul, Anup
    Pellerito, Lorenzo
    Scopelliti, Michelangelo
    Duthie, Andrew
    de Vos, Dick
    Verma, Rajeshwar P.
    Englert, Ulli
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 2012, 107 (01) : 119 - 128
  • [7] Molecular basis of the interaction of novel tributyltin(IV) 2/4-[(E)-2-(aryl)-1-diazenyl] benzoates endowed with an improved cytotoxic profile: Synthesis, structure, biological efficacy and QSAR studies
    Baul, Tushar S. Basu
    Paul, Anup
    Pellerito, Lorenzo
    Scopelliti, Michelangelo
    Pellerito, Claudia
    Singh, Palwinder
    Verma, Pooja
    Duthie, Andrew
    de Vos, Dick
    Verma, Rajeshwar P.
    Englert, Ulli
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 2010, 104 (09) : 950 - 966
  • [8] EFFECTS OF ALKYLTIN COMPOUNDS ON HYDROGEN-OXIDIZING ANAEROBIC-BACTERIA
    BELAY, N
    RAJAGOPAL, BS
    DANIELS, L
    [J]. CURRENT MICROBIOLOGY, 1990, 20 (05) : 329 - 334
  • [9] BERALDO H, 2008, TIN CHEM FUNDAMENTAL, P443
  • [10] DETERMINING CHEMICAL TOXICITY TO AQUATIC SPECIES
    BLUM, DJW
    SPEECE, RE
    [J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1990, 24 (03) : 284 - 293
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