Multiple Sclerosis on Steroids

被引：0

作者：

Johnson, Matthew S. ^{[1
,2
,3
]}

Lee, Michael S. ^{[1
,2
,3
]}

Younge, Brian R. ^{[4
]}

Purvin, Valerie ^{[5
,6
]}

机构：

[1] Univ Minnesota, Dept Ophthalmol, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Dept Neurol, Minneapolis, MN 55455 USA

[3] Univ Minnesota, Dept Neurosurg, Minneapolis, MN 55455 USA

[4] Mayo Clin, Dept Ophthalmol, Rochester, MN USA

[5] Indiana Univ, Med Ctr, Indianapolis, IN USA

[6] Indiana Univ, Midwest Eye Inst, Indianapolis, IN 46204 USA

来源：

SURVEY OF OPHTHALMOLOGY | 2010年 / 55卷 / 05期

关键词：

bilateral visual loss; fulminant; Marburg; multiple sclerosis; optic neuritis; treatment; ISCHEMIC OPTIC NEUROPATHY; INFLAMMATORY DEMYELINATING DISORDERS; ATTACK-RELATED SEVERITY; NEUROMYELITIS-OPTICA; NERVE ENHANCEMENT; MARBURGS TYPE; ABNORMALITIES; NEURITIS; SPECTRUM; CHIASM;

D O I：

10.1016/j.survophthal.2009.11.002

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed. (Surv Ophthalmol 55:460-466, 2010. (C) 2010 Elsevier Inc. All rights reserved.)

引用

页码：460 / 466

页数：7

共 24 条

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