A case of eosinophilic granulomatosis with polyangiitis as a mimicker of IgG4-related disease

被引:6
作者
Kanda, Ryuichiro [1 ]
Kubo, Satoshi [1 ]
Nakano, Kazuhisa [1 ]
Kawabe, Akio [1 ]
Nawata, Aya [1 ]
Hanami, Kentaro [1 ]
Nakayamada, Shingo [1 ]
Tanaka, Yoshiya [1 ]
机构
[1] Univ Occupat & Environm Hlth, Sch Med, Dept Internal Med 1, Kitakyushu, Fukuoka, Japan
基金
日本学术振兴会;
关键词
IgG-related disease; IgG4-related kidney disease; Eosinophilic granulomatosis with polyangiitis; Bird's eye pattern; Storiform fibrosis; CHURG-STRAUSS-SYNDROME; TUBULOINTERSTITIAL NEPHRITIS; IGG4; ANTIBODIES;
D O I
10.1080/24725625.2020.1759200
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 62-year-old woman was admitted to our hospital because of fever, renal dysfunction, eosinophilia, and the presence of MPO-ANCA. Based on the renal pathological examination which showed granuloma lesion with eosinophils and crescentic glomerulonephritis, eosinophilic granulomatosis with polyangiitis (EGPA) was diagnosed. On the other hand, laboratory examination showed elevated serum IgG4 levels and renal pathological examination showed marked lymphoplasmacytic infiltration and fibrosis surrounding nest "Bird's eye pattern," which were characteristic of IgG4-related kidney disease (IgG4-RKD). Because there are cases when EGPA has clinical features of IgG4-RKD, we should be careful about diagnoses of IgG4-RKD in patients with EGPA.
引用
收藏
页码:278 / 282
页数:5
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