Can we reduce the risk of dementia?

被引：7

作者：

Robertson, M. ^{[1
]}

Seaton, A. ^{[2
]}

Whalley, L. J. ^{[2
]}

机构：

[1] Univ Highlands & Isl, Perth Coll, Perth PH1 2NX, Scotland

[2] Univ Aberdeen, Inst Appl Hlth Sci, Aberdeen AB25 2ZH, Scotland

来源：

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2015年 / 108卷 / 02期

关键词：

ALZHEIMERS-DISEASE; COGNITIVE IMPAIRMENT; VASCULAR-DEMENTIA; DEPRESSION; OLDER; PREVALENCE; DECLINE; STROKE;

D O I：

10.1093/qjmed/hcu072

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Public health and therapeutic measures to reduce cardiac and stroke risk may already be reducing risks of dementia in populations. In routine clinical care, dementia risk could be further reduced by optimized management of delirium, depressive disorders, traumatic brain injury and stroke. These are opportunities to minimize risk of progression to dementia during acute care and subsequent rehabilitation. Although interventions to protect against progress to dementia may be of small effect in each clinical situation, awareness of dementia risk and appropriate steps to reduce that risk should contribute to an overall reduction in the incidence of dementia.

引用

页码：93 / 97

页数：5

共 25 条

[1] Depression and Alzheimer's Disease: Is Stress the Initiating Factor in a Common Neuropathological Cascade? [J].

Aznar, Susana ;

Knudsen, Gitte M. .

JOURNAL OF ALZHEIMERS DISEASE, 2011, 23 (02) :177-193

[2]

Barnes DE, 2012, ARCH GEN PSYCHIAT, V69, P493, DOI 10.1001/archgenpsychiatry.2011.1481

[3] The projected effect of risk factor reduction on Alzheimer's disease prevalence [J].

Barnes, Deborah E. ;

Yaffe, Kristine .

LANCET NEUROLOGY, 2011, 10 (09) :819-828

[4] Prevention of Decline in Cognition after Stroke Trial (PODCAST): a study protocol for a factorial randomised controlled trial of intensive versus guideline lowering of blood pressure and lipids [J].

Blackburn, Daniel J. ;

Krishnan, Kailash ;

Fox, Lydia ;

Ballard, Clive ;

Burns, Alistair ;

Ford, Gary A. ;

Mant, Jonathan ;

Passmore, Peter ;

Pocock, Stuart ;

Reckless, John ;

Sprigg, Nikola ;

Stewart, Rob ;

Wardlaw, Joanna ;

Bath, Philip M. W. .

TRIALS, 2013, 14

[5] Much of Late Life Cognitive Decline Is Not due to Common Neurodegenerative Pathologies [J].

Boyle, Patricia A. ;

Wilson, Robert S. ;

Yu, Lei ;

Barr, Alasdair M. ;

Honer, William G. ;

Schneider, Julie A. ;

Bennett, David A. .

ANNALS OF NEUROLOGY, 2013, 74 (03) :478-489

[6] Depression as a Risk Factor or Prodromal Feature for Dementia? Findings in a Population-Based Sample of Swedish Twins [J].

Brommelhoff, Jessica A. ;

Gatz, Margaret ;

Johansson, Boo ;

McArdle, John J. ;

Fratiglioni, Laura ;

Pedersen, Nancy L. .

PSYCHOLOGY AND AGING, 2009, 24 (02) :373-384

[7] Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart [J].

Christensen, Kaare ;

Thinggaard, Mikael ;

Oksuzyan, Anna ;

Steenstrup, Troels ;

Andersen-Ranberg, Karen ;

Jeune, Bernard ;

McGue, Matt ;

Vaupel, James W. .

LANCET, 2013, 382 (9903) :1507-1513

[8] Drug repositioning for Alzheimer's disease [J].

Corbett, Anne ;

Pickett, James ;

Burns, Alistair ;

Corcoran, Jonathan ;

Dunnett, Stephen B. ;

Edison, Paul ;

Hagan, Jim J. ;

Holmes, Clive ;

Jones, Emma ;

Katona, Cornelius ;

Kearns, Ian ;

Kehoe, Patrick ;

Mudher, Amrit ;

Passmore, Anthony ;

Shepherd, Nicola ;

Walsh, Frank ;

Ballard, Clive .

NATURE REVIEWS DRUG DISCOVERY, 2012, 11 (11) :833-846

[9] Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies [J].

Diniz, Breno S. ;

Butters, Meryl A. ;

Albert, Steven M. ;

Dew, Mary Amanda ;

Reynolds, Charles F., III .

BRITISH JOURNAL OF PSYCHIATRY, 2013, 202 (05) :329-335

[10] Vascular Contributions to Cognitive Impairment and Dementia A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association [J].

Gorelick, Philip B. ;

Scuteri, Angelo ;

Black, Sandra E. ;

DeCarli, Charles ;

Greenberg, Steven M. ;

Iadecola, Costantino ;

Launer, Lenore J. ;

Laurent, Stephane ;

Lopez, Oscar L. ;

Nyenhuis, David ;

Petersen, Ronald C. ;

Schneider, Julie A. ;

Tzourio, Christophe ;

Arnett, Donna K. ;

Bennett, David A. ;

Chui, Helena C. ;

Higashida, Randall T. ;

Lindquist, Ruth ;

Nilsson, Peter M. ;

Roman, Gustavo C. ;

Sellke, Frank W. ;

Seshadri, Sudha .

STROKE, 2011, 42 (09) :2672-2713

← 1 2 3 →