Fly fishing for GSTs: a unified nomenclature for mammalian and insect glutathione transferases

被引:0
作者
Chelvanayagam, G
Parker, MW
Board, PG
机构
[1] Australian Natl Univ, John Curtin Sch Med Res, Human Genet Grp, Canberra, ACT 0200, Australia
[2] St Vincents Inst Med Res, Ian Potter Fdn Prot Crystallog Lab, Melbourne, Vic 3065, Australia
关键词
glutathione transferase; GST classes; insect GSTs; GST nomenclature;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Previously, due to the paucity of sequence data, only two broad classes of glutathione transferases (GSTs) were identified in insects. The recent completion of the sequencing of the Drosophila melanogaster genome has allowed the identification of a considerable number of insect GSTs via a systematic comparison of the genome with sequences from established GST classes. Strikingly, many GST classes found in mammals also occur in Drosophila. These results suggest that the nomenclature originally proposed for invertebrates GSTs, can be extended to harmonise with that used for humans and other species. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:256 / 260
页数:5
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