Malaria eradication and elimination: views on how to translate a vision into reality

被引:97
作者
Tanner, Marcel [1 ,1 ]
Greenwood, Brian [2 ]
Whitty, Christopher J. M. [2 ]
Ansah, Evelyn K. [3 ]
Price, Ric N. [4 ,5 ]
Dondorp, Arjen M. [5 ]
von Seidlein, Lorenz [5 ,6 ]
Baird, J. Kevin [5 ,7 ]
Beeson, James G. [8 ,9 ]
Fowkes, Freya J. I. [8 ,10 ,11 ,12 ]
Hemingway, Janet [13 ]
Marsh, Kevin [14 ]
Osier, Faith [15 ]
机构
[1] Univ Basel, Basel, Switzerland
[2] London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London WC1, England
[3] Ghana Hlth Serv, Div Res & Dev, Accra, Ghana
[4] Charles Darwin Univ, Menzies Sch Hlth Res, Global & Trop Hlth Div, Darwin, NT 0909, Australia
[5] Univ Oxford, Ctr Trop Med & Global Hlth, Nuffield Dept Med, Oxford, England
[6] Mahidol Univ, Fac Trop Med, Mahidol Oxford Res Unit, Bangkok, Thailand
[7] Eijkman Oxford Clin Res Unit, Jakarta 10430, Indonesia
[8] Burnet Inst, Melbourne, Vic 3004, Australia
[9] Monash Univ, Dept Microbiol, Clayton, Vic 3800, Australia
[10] Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia
[11] Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic 3004, Australia
[12] Monash Univ, Dept Infect Dis, Melbourne, Vic 3004, Australia
[13] Univ Liverpool, Liverpool Sch Trop Med, Liverpool L3 5QA, Merseyside, England
[14] African Acad Sci, Nairobi, Kenya
[15] KEMRI Ctr Geog Med Res Coast, Kilifi, Kenya
基金
澳大利亚国家健康与医学研究理事会; 英国医学研究理事会;
关键词
Malaria; Plasmodium falciparum; Plasmodium vivax; Eradication; Epidemiology; Rapid diagnostics; Drug resistance; Mass drug administration; Vaccines; Vector control; Capacity building; TRANSMISSION-BLOCKING VACCINE; RAPID DIAGNOSTIC-TESTS; PLASMODIUM-FALCIPARUM MALARIA; VIVAX MALARIA; DOUBLE-BLIND; CHLOROQUINE RESISTANCE; ARTEMISININ RESISTANCE; RISK-FACTORS; OPEN-LABEL; FOLLOW-UP;
D O I
10.1186/s12916-015-0384-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although global efforts in the past decade have halved the number of deaths due to malaria, there are still an estimated 219 million cases of malaria a year, causing more than half a million deaths. In this forum article, we asked experts working in malaria research and control to discuss the ways in which malaria might eventually be eradicated. Their collective views highlight the challenges and opportunities, and explain how multi-factorial and integrated processes could eventually make malaria eradication a reality.
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