Stereoselective synthesis of 1,3,5-trienes from alkynones and allyl carbonyl compounds through C-C σ-bond cleavage under transition-metal-free conditions

被引：3
作者：
Cheng, Lu [1 ]
Wang, Mengdan [1 ]
Yang, Yajie [1 ]
Wang, Zongkang [1 ]
Zhu, Yilin [1 ]
Kong, Lingkai [2 ]
Li, Yanzhong [1 ]
机构：
[1] East China Normal Univ, Sch Chem & Mol Engn, 500 Dongchuan Rd, Shanghai 200241, Peoples R China
[2] Linyi Univ, Sch Chem & Chem Engn, Shuangling Rd, Linyi 276000, Shandong, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 12期
基金：
中国国家自然科学基金;
关键词：
CONJUGATED TRIENES; STEREOCONTROLLED SYNTHESIS; RING EXPANSION; INSERTION; ALKYNES; CONVENIENT; ESTERS; OLIGOMERS; ALCOHOLS; ANALOGS;
D O I：
10.1039/d2qo00617k
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An atom-economical transition-metal-free protocol for the stereoselective synthesis of conjugated trienes has been developed. These transformations were realized through base promoted C-C sigma-bond cleavage reactions of allyl carbonyl compounds. This methodology efficiently constructs a broad range of conjugated trienes with the advantages of mild reaction conditions, low cost and operational simplicity.
引用
收藏
页码：3354 / 3359
页数：6
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