Stereoselective synthesis of 1,3,5-trienes from alkynones and allyl carbonyl compounds through C-C σ-bond cleavage under transition-metal-free conditions

被引：3

作者：

Cheng, Lu ^{[1
]}

Wang, Mengdan ^{[1
]}

Yang, Yajie ^{[1
]}

Wang, Zongkang ^{[1
]}

Zhu, Yilin ^{[1
]}

Kong, Lingkai ^{[2
]}

Li, Yanzhong ^{[1
]}

机构：

[1] East China Normal Univ, Sch Chem & Mol Engn, 500 Dongchuan Rd, Shanghai 200241, Peoples R China

[2] Linyi Univ, Sch Chem & Chem Engn, Shuangling Rd, Linyi 276000, Shandong, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 12期

基金：

中国国家自然科学基金;

关键词：

CONJUGATED TRIENES; STEREOCONTROLLED SYNTHESIS; RING EXPANSION; INSERTION; ALKYNES; CONVENIENT; ESTERS; OLIGOMERS; ALCOHOLS; ANALOGS;

D O I：

10.1039/d2qo00617k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An atom-economical transition-metal-free protocol for the stereoselective synthesis of conjugated trienes has been developed. These transformations were realized through base promoted C-C sigma-bond cleavage reactions of allyl carbonyl compounds. This methodology efficiently constructs a broad range of conjugated trienes with the advantages of mild reaction conditions, low cost and operational simplicity.

引用

页码：3354 / 3359

页数：6

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