Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia

被引:9
作者
Assadi, Mitra [1 ]
Leone, Paola [2 ]
Veloski, J. Jon [3 ]
Schwartzman, Robert J. [4 ]
Janson, Christopher G. [2 ]
Campellone, Joseph V. [1 ]
机构
[1] Cooper Univ Hosp, Robert Wood Johnson Med Sch, Dept Med, Div Neurol, Camden, NJ USA
[2] Cooper Univ Hosp, Robert Wood Johnson Med Sch, Dept Neurol & Mol Genet, Camden, NJ USA
[3] Thomas Jefferson Univ, Jefferson Med Coll, Ctr Res Med Educ & Hlth Care, Philadelphia, PA 19107 USA
[4] Drexel Univ Hosp, Dept Neurol, Philadelphia, PA USA
关键词
ataxia; SCA; clinical assessment;
D O I
10.1016/j.jns.2007.11.016
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:136 / 139
页数:4
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