A Clean, Highly Efficient and One-Pot Green Synthesis of Aryl/Alkyl/Heteroaryl-Substituted Bis(6-amino-1,3-dimethyluracil-5-yl)methanes in Water

被引：44
作者：
Das, Subrata [1 ]
Thakur, Ashim Jyoti [1 ]
机构：
[1] Tezpur Univ, Dept Chem Sci, Tezpur 784028, Assam, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 2011卷 / 12期
关键词：
Nitrogen heterocycles; Green chemistry; Heterocycles; Water chemistry; CROSS-METATHESIS REACTIONS; C-H ACTIVATION; ROOM-TEMPERATURE; ORGANIC-REACTIONS; ADENOSINE A(1); URACIL; DERIVATIVES; CHEMISTRY; CATALYST; DNA;
D O I：
10.1002/ejoc.201001581
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient green synthesis of aryl/alkyl/heteroaryl-substituted bis(6-amino-1,3-dimethyluracil-5-yl)methanes by the condensation of 6-amino-1,3-dimethyluracil with aldehydes (aromatic, aliphatic and heterocyclic) in water at room temperature is described. No dehydrating agent, heat, catalyst, surfactant or additive was used. The structures of the compounds were established by spectroscopic methods and single-crystal X-ray crystallography.
引用
收藏
页码：2301 / 2308
页数：8
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