Self-Assembled Peptide Nanoarchitectures: Applications and Future Aspects

被引：13

作者：

Sharma, Prem Prakash ^{[1
]}

Rathi, Brijesh ^{[1
]}

Rodrigues, Joao ^{[2
]}

Gorobets, Nikolay Yu. ^{[3
]}

机构：

[1] Univ Delhi, Hansraj Coll, Dept Chem, Delhi 110007, India

[2] Univ,Madeira, MMRG, FCT Natl Res Unit UID0674, Ctr Quim Madeira, P-9020105 Funchal, Portugal

[3] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, Dept Chem Heterocycl Cpds, UA-61001 Kharkov, Ukraine

来源：

CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2015年 / 15卷 / 13期

关键词：

Peptide self-assembly; Peptide nanoube; Peptide nanofiber; Peptide nanosphere; Peptide hydrogel; Peptide dendrimer; AMYLOID FIBRIL FORMATION; BUILDING-BLOCKS; COMPLEMENTARY OLIGOPEPTIDE; ALPHA-HELIX; GOLDEN-AGE; NANOSTRUCTURES; NANOTUBES; DRUG; DESIGN; DELIVERY;

D O I：

10.2174/1568026615666150408105711

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Among the diversity of natural and synthetic compounds being studied and applied for human welfare, peptides able to develop nanostructures are currently under special attention of scientists. In this review, we focus on such properties of peptides and various kinds of intramolecular interactions allowing their ability to form different shapes of nanoassemblies. We have also discussed the applications of self-assembled peptides in various biomedical fields where they can be employed as cargo to target delivery of drugs, genes, in tissue engineering, regenerative medicines, and biosensors.

引用

页码：1268 / 1289

页数：22

共 152 条

[1] Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers [J].

Accardo, Antonella ;

Tesauro, Diego ;

Mangiapia, Gaetano ;

Pedone, Carlo ;

Morelli, Giancarlo .

BIOPOLYMERS, 2007, 88 (02) :115-121

[2]

Adhikari Bimalendu, 2011, Journal of the Indian Institute of Science, V91, P471

[3] Thermal and chemical stability of diphenylalanine peptide nanotubes: Implications for nanotechnological applications [J].

Adler-Abramovich, L ;

Reches, M ;

Sedman, VL ;

Allen, S ;

Tendler, SJB ;

Gazit, E .

LANGMUIR, 2006, 22 (03) :1313-1320

[4] Controlled patterning of peptide nanotubes and nanospheres using inkjet printing technology [J].

Adler-Abramovich, Lihi ;

Gazit, Ehud .

JOURNAL OF PEPTIDE SCIENCE, 2008, 14 (02) :217-223

[5] Responsive gels formed by the spontaneous self-assembly of peptides into polymeric beta-sheet tapes [J].

Aggeli, A ;

Bell, M ;

Boden, N ;

Keen, JN ;

Knowles, PF ;

McLeish, TCB ;

Pitkeathly, M ;

Radford, SE .

NATURE, 1997, 386 (6622) :259-262

[6] Engineering of peptide beta-sheet nanotapes [J].

Aggeli, A ;

Bell, M ;

Boden, N ;

Keen, JN ;

McLeish, TCB ;

Nyrkova, I ;

Radford, SE ;

Semenov, A .

JOURNAL OF MATERIALS CHEMISTRY, 1997, 7 (07) :1135-1145

[7] Novel dipeptide nanoparticles for effective curcumin delivery [J].

Alam, Shadab ;

Panda, Jiban J. ;

Chauhan, Virander S. .

INTERNATIONAL JOURNAL OF NANOMEDICINE, 2012, 7 :4207-4222

[8] Elementary Building Blocks of Self-Assembled Peptide Nanotubes [J].

Amdursky, Nadav ;

Molotskii, Michel ;

Gazit, Ehud ;

Rosenman, Gil .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (44) :15632-15636

[9] New cyclic peptide assemblies with hydrophobic cavities:: The structural and thermodynamic basis of a new class of peptide nanotubes [J].

Amorín, M ;

Castedo, L ;

Granja, JR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (10) :2844-2845

[10] Peptide-Based Nanostructures for Cancer Diagnosis and Therapy [J].

An, Linna ;

Gilani, M. Rehan H. Shah ;

Liang, Gaolin .

CURRENT MEDICINAL CHEMISTRY, 2014, 21 (21) :2453-2466

← 1 2 3 4 5 6 7 8 9 10 →