A multicomponent formal [1+2+1+2]-cycloaddition for the synthesis of dihydropyridines

被引：27
作者：
Girling, P. Ricardo [1 ]
Batsanov, Andrei S. [1 ]
Shen, Hong C. [2 ]
Whiting, Andrew [1 ]
机构：
[1] Univ Durham, Dept Chem, Ctr Sustainable Chem Proc, Durham DH1 3LE, England
[2] Merck & Co Inc, Rahway, NJ 07065 USA
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 40期
基金：
英国工程与自然科学研究理事会;
关键词：
DIELS-ALDER REACTION; N-ARYL IMINES; ABSOLUTE STEREOCHEMISTRY; DANISHEFSKYS DIENE; DIASTEREOSELECTIVITY; ASSIGNMENT; CHEMISTRY; ACETATE;
D O I：
10.1039/c2cc31495a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of methoxyvinylmethylketone with different amines and aldehydes under Lewis-acid catalysed conditions results in a novel, formal, step-wise [1+2+1+2]-cycloaddition to give dihydropyridine products.
引用
收藏
页码：4893 / 4895
页数：3
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