Telephone based cognitive-behavioral screening for frontotemporal changes in patients with amyotrophic lateral sclerosis (ALS)

被引:17
作者
Christodoulou, Georgia [1 ]
Gennings, Chris [2 ]
Hupf, Jonathan [1 ]
Factor-Litvak, Pam [3 ]
Murphy, Jennifer [4 ]
Goetz, Raymond R. [5 ,6 ]
Mitsumoto, Hiroshi [1 ]
机构
[1] Columbia Univ, Dept Neurol, Med Ctr, Columbia MDA ALS Res Ctr, 710 West 168th St, New York, NY 10032 USA
[2] Mt Sinai Hosp, New York, NY 10029 USA
[3] Columbia Univ, Sch Publ Hlth, Dept Epidemiol, New York, NY USA
[4] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[5] Columbia Univ, New York State Psychiat Inst, New York, NY USA
[6] Columbia Univ, Dept Psychiat, New York, NY USA
关键词
ALS; FTD; telephone; cognitive testing; FRONTAL-LOBE IMPAIRMENT; MINI-MENTAL-STATE; DEMENTIA; DYSFUNCTION; CONTINUUM; TESTS; EXAM; TOOL; FTD;
D O I
10.3109/21678421.2016.1173703
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Our objective was to establish a valid and reliable battery of measures to evaluate frontotemporal dementia (FTD) in patients with ALS over the telephone. Thirty-one subjects were administered either in-person or by telephone-based screening followed by the opposite mode of testing two weeks later, using a modified version of the UCSF Cognitive Screening Battery. Equivalence testing was performed for in-person and telephone based tests. The standard ALS Cognitive Behavioral Screen (ALS-CBS) showed statistical equivalence at the 5% significance level compared to a revised phone version of the ALS-CBS. In addition, the Controlled Oral Word Association Test (COWAT) and Center for Neurologic Study-Lability Scale (CNS-LS) were also found to be equivalent at the 5% and 10% significance level, respectively. Similarly, the Mini-Mental State Examination (MMSE) and the well-established Telephone Interview for Cognitive Status (TICS) were also statistically equivalent. Equivalence could not be claimed for the ALS-Frontal Behavioral Inventory (ALS-FBI) caregiver interview and the Written Verbal Fluency Index (WVFI). In conclusion, our study suggests that telephone-based versions of the ALS-CBS, COWAT, and CNS-LS may offer clinicians valid tools to detect frontotemporal changes in the ALS population. Development of telephone based cognitive testing for ALS could become an integral resource for population based research in the future.
引用
收藏
页码:482 / 488
页数:7
相关论文
共 32 条
[1]   Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS) [J].
Abrahams, S ;
Leigh, PN ;
Harvey, A ;
Vythelingum, GN ;
Grisé, D ;
Goldstein, LH .
NEUROPSYCHOLOGIA, 2000, 38 (06) :734-747
[2]   Screening for cognition and behaviour changes in ALS [J].
Abrahams, Sharon ;
Newton, Judith ;
Niven, Elaine ;
Foley, Jennifer ;
Bak, Thomas H. .
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2014, 15 (1-2) :9-14
[3]  
[Anonymous], 2015, ALS CBS MANUAL INSTR
[4]  
Benton A.L., 1994, MULTILINGUAL APHASIA
[5]   Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS [J].
Callister, Janis-Bennion ;
Pickering-Brown, Stuart M. .
EXPERIMENTAL NEUROLOGY, 2014, 262 :84-90
[6]   Telephone-based screening tools for mild cognitive impairment and dementia in aging studies: a review of validated instruments [J].
Castanho, Teresa C. ;
Amorim, Liliana ;
Zihl, Joseph ;
Palha, Joana A. ;
Sousa, Nuno ;
Santos, Nadine C. .
FRONTIERS IN AGING NEUROSCIENCE, 2014, 6
[7]   FTD and ALS: A Tale of Two Diseases [J].
Ferrari, R. ;
Kapogiannis, D. ;
Huey, E. D. ;
Momeni, P. .
CURRENT ALZHEIMER RESEARCH, 2011, 8 (03) :273-294
[8]   Penn State screen exam for the detection of frontal and temporal dysfunction syndromes: Application to ALS [J].
Flaherty-Craig, Claire ;
Brothers, Allyson ;
Dearman, Brandon ;
Eslinger, Paul ;
Simmons, Zachary .
AMYOTROPHIC LATERAL SCLEROSIS, 2009, 10 (02) :107-112
[9]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[10]   Dementia and cognitive impairment in amyotrophic lateral sclerosis: a review [J].
Giordana, Maria Teresa ;
Ferrero, Patrizia ;
Grifoni, Silvia ;
Pellerino, Alessia ;
Naldi, Andrea ;
Montuschi, Anna .
NEUROLOGICAL SCIENCES, 2011, 32 (01) :9-16