Oral verapamil effectively suppressed complex ventricular arrhythmias and unmasked U waves in a patient with Andersen-Tawil syndrome

被引：14

作者：

Erdogan, Okan ^{[1
]}

Aksoy, Alper ^{[2
]}

Turgut, Nilda ^{[2
]}

Durusoy, Elcim ^{[2
]}

Samsa, Murat ^{[2
]}

Altun, Armagan ^{[2
]}

机构：

[1] Marmara Univ, Tip Fak Hastanesi Altunizade, Sch Med, Dept Cardiol, Istanbul, Turkey

[2] Trakya Univ, Sch Med, Dept Cardiol, Edirne, Turkey

来源：

JOURNAL OF ELECTROCARDIOLOGY | 2008年 / 41卷 / 04期

关键词：

Andersen-Tawil; verapamil; bidirectional VT; U wave; long QT; therapy; sudden death;

D O I：

10.1016/j.jelectrocard.2008.02.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Andersen-Tawil syndrome (ATS) is a rare, heterogeneous, autosomal dominant, or sporadic disorder characterized by the clinical triad of periodic paralysis, dysmorphic features, and ventricular arrhythmias such as bidirectional ventricular tachycardia (BVT). We present a case of an elderly patient with ATS whose symptomatic ventricular arrhythmias including BVT were effectively suppressed by oral verapamil therapy. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：325 / 328

页数：4

共 8 条

[1] Polymorphic ventricular tachycardia and KCNJ2 mutations [J].

Chun, TUH ;

Epstein, MR ;

Dick, M ;

Andelfinger, G ;

Ballester, L ;

Vanoye, CG ;

George, AL ;

Benson, DW .

HEART RHYTHM, 2004, 1 (02) :235-241

[2]

Efremidis Michalis, 2006, Int J Cardiol, V112, pe45, DOI 10.1016/j.ijcard.2006.02.028

[3] Suppression of bidirectional ventricular tachycardia and unmasking of prolonged QT interval with verapamil in Andersen's syndrome [J].

Kannankeril, PJ ;

Roden, DM ;

Fish, FA .

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2004, 15 (01) :119-119

[4] Sudden cardiac death in Andersen-Tawil syndrome [J].

Peters, Stefan ;

Schulze-Bahr, Eric ;

Etheridge, Susan P. ;

Tristani-Firouzi, Martin .

EUROPACE, 2007, 9 (03) :162-166

[5]

Smith CR, 2006, J INSECT SCI, V6, DOI 10.1673/2006_06_32.1

[6] Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome) [J].

Tristani-Firouzi, M ;

Jensen, JL ;

Donaldson, MR ;

Sansone, V ;

Meola, G ;

Hahn, A ;

Bendahhou, S ;

Kwiecinski, H ;

Fidzianska, A ;

Plaster, N ;

Fu, YH ;

Ptacek, LJ ;

Tawil, R .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 110 (03) :381-388

[7] The primary periodic paralyses: diagnosis, pathogenesis and treatment [J].

Venance, SL ;

Cannon, SC ;

Fialho, D ;

Fontaine, B ;

Hanna, MG ;

Ptacek, LJ ;

Tristani-Firouzi, M ;

Tawil, R ;

Griggs, RC .

BRAIN, 2006, 129 :8-17

[8] Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations -: Characteristic T-U-wave patterns predict the KCNJ2 genotype [J].

Zhang, L ;

Benson, DW ;

Tristani-Firouzi, M ;

Ptacek, LJ ;

Tawil, R ;

Schwartz, PJ ;

George, AL ;

Horie, M ;

Andelfinger, G ;

Snow, GL ;

Fu, YH ;

Ackerman, MJ ;

Vincent, GM .

CIRCULATION, 2005, 111 (21) :2720-2726

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