SYNTHESIS OF COPOLYMERS BASED ON 2-VINYLPYRIDINE WITH ANTIBACTERIAL PROPERTIES

被引:6
|
作者
Valle, Aline S. S. [1 ]
Costa, Luciana C. [1 ]
Marques, Monica R. C. [1 ]
Silva, Camila L. P. [1 ]
de Santa Maria, Luiz Claudio [1 ]
Mercon, Fabio [2 ]
de Aguiar, Alcino Palermo [3 ]
机构
[1] Univ Estado Rio de Janeiro, Inst Quim, Dept Quim Organ, BR-20559900 Rio De Janeiro, Brazil
[2] Univ Estado Rio de Janeiro, Inst Quim, Dept Tecnol Proc Bioquim, BR-20559900 Rio De Janeiro, Brazil
[3] Inst Mil Engn, Dept Engn Quim, BR-22290270 Rio De Janeiro, Brazil
来源
QUIMICA NOVA | 2011年 / 34卷 / 04期
关键词
biocidal polymers; 2-vinylpyridine-styrene-divinylbenzene copolymers; iodine; BEADS; POLYSTYRENES; SURFACE; RESINS;
D O I
10.1590/S0100-40422011000400005
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
SYNTHESIS OF COPOLYMERS BASED ON 2-VINYLPYRIDINE WITH ANTIBACTERIAL PROPERTIES. We report the development of two copolymers based on 2-vinylpyridine, styrene and divinylbenzene (2Vpy-Sty-DVB) with different porosity degrees. The copolymers were subsequently quaternized with methyl iodide. To prepare charge transfer complexes, the unmodified copolymers and their derivatives quaternized with methyl iodine were impregnated with iodine. The antibacterial properties of the polymers were evaluated in dilutions ranging from 10(2) to 10(7) cells/mL of the auxotrophic OHd5-K12 Escherichia coli strain. It was possible to obtain materials with complete antibacterial activity even in the highest cell concentrations tested.
引用
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页码:577 / U20
页数:9
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