Theranostic Gold Nanomicelles made from Biocompatible Comb-like Polymers for Thermochemotherapy and Multifunctional Imaging with Rapid Clearance

被引：144

作者：

Deng, Heng ^{[1
,2
]}

Dai, Fengying ^{[1
]}

Ma, Guanghui ^{[1
]}

Zhang, Xin ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China

[2] Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 24期

基金：

北京市自然科学基金; 中国国家自然科学基金;

关键词：

PHOTOTHERMAL THERAPY; PLASMONIC VESICLES; NANOPARTICLES; TOMOGRAPHY; AGENT; RESONANCE; NANOCAGES; NANORODS; RELEASE; CARRIER;

D O I：

10.1002/adma.201501420

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new generation of photothermal theranostic agents based on assembling 6 nm gold nanoparticles (AuNPs) is developed by using a novel comb-like amphipathic polymer as the template. The small AuNPs are assembled into DOX@gold nanomicelles, which show strong absorbance in the near-infrared region, for multimodal bioimaging and highly effective in vivo chemotherapy and photothermal therapy.

引用

页码：3645 / 3653

页数：9

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