Influence of epilepsy surgery on developmental outcomes in children

被引：41

作者：

Braun, Kees P. J. ^{[1
]}

机构：

[1] Univ Utrecht, Univ Med Ctr Utrecht, Brain Ctr, Utrecht, Netherlands

来源：

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY | 2020年 / 24卷

关键词：

Epilepsy surgery; Development; Cognitive outcome; Children; ANTIEPILEPTIC DRUG-WITHDRAWAL; INTELLIGENCE QUOTIENT; SEIZURE; HEMISPHERECTOMY;

D O I：

10.1016/j.ejpn.2019.12.014

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Epilepsy surgery is the most effective treatment option for children with refractory focal lesional epilepsy, with seizure-freedom rates exceeding 70% two years after surgery. Although numbers of procedures in children are increasing over time, epilepsy surgery remains underutilized. Particularly in young children with developmental delay, arrest, or even regression, surgery can improve cognitive outcome. Many factors determine eventual developmental abilities, of which epilepsy duration is the most important modifiable predictor. Earlier surgery is not only associated with higher seizure-freedom rates, it also improves postoperative developmental outcomes. Every child with focal lesional epilepsy should therefore be referred early, to evaluate the possibilities of epilepsy surgery. (C) 2019 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：40 / 42

页数：3

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