Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer

被引：72

作者：

Galvao, D. A.

Taaffe, D. R.

Spry, N.

Newton, R. U.

机构：

[1] Edith Cowan Univ, Vario Hlth Inst, Sch Exercise Biomed & Hlth Sci, Joondalup, WA 6027, Australia

[2] Univ Queensland, Sch Human Movement Studies, Brisbane, Qld, Australia

[3] Sir Charles Gairdner Hosp, Dept Radiat Oncol, Nedlands, WA 6009, Australia

[4] Univ Western Australia, Fac Med, Nedlands, WA 6009, Australia

来源：

PROSTATE CANCER AND PROSTATIC DISEASES | 2007年 / 10卷 / 04期

关键词：

androgen antagonists; skeletal muscle; exercise;

D O I：

10.1038/sj.pcan.4500975

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects during and following therapy. In this review, we discuss common morphological and physiological ADT-related side effects or 'Androgen Deprivation and Sarcopenia-Related Disorders' and the existing clinical trials incorporating physical exercise in prostate cancer patients receiving active therapy. Further, training concepts and guidelines are provided for prescribing resistance exercise programs for this population.

引用

页码：340 / 346

页数：7

共 44 条

[1] Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy [J].