Protein-Pacing Caloric-Restriction Enhances Body Composition Similarly in Obese Men and Women during Weight Loss and Sustains Efficacy during Long-Term Weight Maintenance

被引:22
作者
Arciero, Paul J. [1 ]
Edmonds, Rohan [1 ]
He, Feng [1 ,2 ]
Ward, Emery [1 ]
Gumpricht, Eric [3 ]
Mohr, Alex [3 ]
Ormsbee, Michael J. [4 ,5 ]
Astrup, Arne [6 ]
机构
[1] Skidmore Coll, Hlth & Exercise Sci Dept, Human Nutr & Metab Lab, Saratoga Springs, NY 12866 USA
[2] Calif State Univ Chico, Dept Kinesiol, Chico, CA 95929 USA
[3] Isagenix Int LLC, Gilbert, AZ 85297 USA
[4] Florida State Univ, Dept Nutr Food & Exercise Sci, Tallahassee, FL 32306 USA
[5] Univ KwaZulu Natal, Dept Biokinet Exercise & Leisure Sci, ZA-4000 Durban, South Africa
[6] Univ Copenhagen, Dept Nutr Exercise & Sports, DK-1017 Copenhagen, Denmark
来源
NUTRIENTS | 2016年 / 8卷 / 08期
关键词
protein-pacing; caloric restriction; intermittent fasting; abdominal obesity; heart healthy; VISCERAL ADIPOSE-TISSUE; LOW-CARBOHYDRATE-DIET; RANDOMIZED-TRIAL; RISK-FACTORS; LEPTIN CONCENTRATIONS; ENERGY RESTRICTION; WHEY-PROTEIN; FAT LOSS; OVERWEIGHT; INTERMITTENT;
D O I
10.3390/nu8080476
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Short-Term protein-pacing (P; similar to 6 meals/day, >30% protein/day) and caloric restriction (CR, similar to 25% energy deficit) improves total (TBF), abdominal (ABF) and visceral (VAT) fat loss, energy expenditure, and biomarkers compared to heart healthy (HH) recommendations (3 meals/day, 15% protein/day) in obese adults. Less is known whether obese men and women respond similarly to P-CR during weight loss (WL) and whether a modified P-CR (mP-CR) is more efficacious than a HH diet during long-term (52 week) weight maintenance (WM). The purposes of this study were to evaluate the efficacy of: (1) P-CR on TBF, ABF, resting metabolic rate (RMR), and biomarkers between obese men and women during WL (weeks 0-12); and (2) mP-CR compared to a HH diet during WM (weeks 13-64). During WL, men (n = 21) and women (n = 19) were assessed for TBF, ABF, VAT, RMR, and biomarkers at weeks 0 (pre) and 12 (post). Men and women had similar reductions (p < 0.01) in weight (10%), TBF (19%), ABF (25%), VAT (33%), glucose (7%-12%), insulin (40%), leptin (>50%) and increase in % lean body mass (9%). RMR (kcals/kg bodyweight) was unchanged and respiratory quotient decreased 9%. Twenty-four subjects (mP-CR, n = 10; HH, n = 14) completed WM. mP-CR regained significantly less body weight (6%), TBF (12%), and ABF (17%) compared to HH (p < 0.05). Our results demonstrate P-CR enhances weight loss, body composition and biomarkers, and maintains these changes for 52-weeks compared to a traditional HH diet.
引用
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页数:19
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