Beyond publication bias

被引:19
作者
Bax, Leon [1 ,2 ,3 ]
Moons, Karel G. [2 ]
机构
[1] Pharsight Corp, Strateg Consulting Serv, Sunnyvale, CA USA
[2] UMC Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[3] Kitasato Univ, Kitasato Clin Res Ctr, Sagamihara, Kanagawa 228, Japan
关键词
Systematic reviews; Meta-analysis; Bias; Publication bias; Evidence dissemination; Evidence-based medicine; DISSEMINATION BIAS; METAANALYSIS; TRIALS;
D O I
10.1016/j.jclinepi.2010.09.003
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
In drug development, clinical medicine, or health policy making, basing one's decisions on a selective part of the available evidence can pose a major threat to the health of patients and the society. If, for example, primarily positive research reports are taken into account, one could wrongfully conclude that a harmful drug is safe. The systematic error introduced by summarizing evidence that is not representative of the available evidence is commonly referred to as "publication bias." Some, however, prefer other terms to refer to the same concept. In this article, we explore the terminology and concepts relevant to this bias and propose a more systematic nomenclature than what is currently used. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:459 / 462
页数:4
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