An update on chronic lung allograft dysfunction

被引：10

作者：

Kotecha, Sakhee ^{[1
]}

Paraskeva, Miranda A. ^{[1
]}

Levin, Kovi ^{[1
]}

Snell, Gregory I. ^{[1
]}

机构：

[1] Alfred Hosp, Lung Transplant Serv, Commercial Rd, Melbourne, Vic 3004, Australia

来源：

ANNALS OF TRANSLATIONAL MEDICINE | 2020年 / 8卷 / 06期

关键词：

Lung transplantation (LTx); chronic lung allograft dysfunction (CLAD); BRONCHIOLITIS OBLITERANS SYNDROME; ANTIBODY-MEDIATED REJECTION; TRANSPLANTATION; CAPACITY; HEART; FIBROELASTOSIS; SURVIVAL;

D O I：

10.21037/atm.2020.01.05

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chronic lung allograft dysfunction (CLAD) remains a significant challenge and the major determinant of morbidity and mortality post lung transplantation (LTx). The definition of CLAD has evolved significantly over the last ten years, reflecting better understanding of pathophysiology and different phenotypes. While there is an agreed consensus approach to CLAD, questions remain regarding the limitations of lung function parameters as well as the role of imaging and histopathology. Here we present a current snapshot of the definition of CLAD, its evolution and future directions.

引用

页数：9

共 39 条

[1] LUNG-FUNCTION TESTING - SELECTION OF REFERENCE VALUES AND INTERPRETATIVE STRATEGIES [J].

不详 .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 144 (05) :1202-1218

[2] Longitudinal Forced Vital Capacity Monitoring as a Prognostic Adjunct after Lung Transplantation [J].

Belloli, Elizabeth A. ;

Wang, Xin ;

Murray, Susan ;

Forrester, Ginia ;

Weyhing, Adrian ;

Lin, Jules ;

Ojo, Tammy ;

Lama, Vibha N. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 192 (02) :209-218

[3] POST-TRANSPLANT OBLITERATIVE BRONCHIOLITIS AND OTHER LATE LUNG SEQUELAE IN HUMAN HEART-LUNG TRANSPLANTATION [J].

BURKE, CM ;

THEODORE, J ;

DAWKINS, KD ;

YOUSEM, SA ;

BLANK, N ;

BILLINGHAM, ME ;

VANKESSEL, A ;

JAMIESON, SW ;

OYER, PE ;

BALDWIN, JC ;

STINSON, EB ;

SHUMWAY, NE ;

ROBIN, ED .

CHEST, 1984, 86 (06) :824-829

[4]

COOPER JD, 1993, J HEART LUNG TRANSPL, V12, P713

[5] Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients [J].

DerHovanessian, Ariss ;

Todd, Jamie L. ;

Zhang, Alice ;

Li, Ning ;

Mayalall, Aradhna ;

Copeland, C. Ashley Finlen ;

Shino, Michael ;

Pavlisko, Elizabeth N. ;

Wallace, W. Dean ;

Gregson, Aric ;

Ross, David J. ;

Saggar, Rajan ;

Lynch, Joseph P., III ;

Belperio, John ;

Snyder, Laurie D. ;

Palmer, Scott M. ;

Weigt, S. Sam .

ANNALS OF THE AMERICAN THORACIC SOCIETY, 2016, 13 (05) :627-635

[6] Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT [J].

Glanville, Allan R. ;

Verleden, Geert M. ;

Todd, Jamie L. ;

Benden, Christian ;

Calabrese, Fiorella ;

Gottlieb, Jens ;

Hachem, Ramsey R. ;

Levine, Deborah ;

Meloni, Federica ;

Palmer, Scott M. ;

Roman, Antonio ;

Sato, Masaaki ;

Singer, Lianne G. ;

Tokman, Sofya ;

Verleden, Stijn E. ;

von der Thusen, Jan ;

Vos, Robin ;

Snell, Gregory .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2019, 38 (05) :483-492

[7] Molecular assessment of rejection and injury in lung transplant biopsies [J].

Halloran, Kieran M. ;

Parkes, Michael D. ;

Chang, Jessica ;

Timofte, Irina L. ;

Snell, Gregory, I ;

Westall, Glen P. ;

Hachem, Ramsey ;

Kreisel, Daniel ;

Trulock, Elbert ;

Roux, Antoine ;

Juvet, Stephen ;

Keshavjee, Shaf ;

Jaksch, Peter ;

Klepetko, Walter ;

Halloran, Philip F. .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2019, 38 (05) :504-513

[8] OPTN/SRTR 2016 Annual Data Report: Kidney [J].

Hart, A. ;

Smith, J. M. ;

Skeans, M. A. ;

Gustafson, S. K. ;

Wilk, A. R. ;

Robinson, A. ;

Wainright, J. L. ;

Haynes, C. R. ;

Snyder, J. J. ;

Kasiske, B. L. ;

Israni, A. K. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2018, 18 :18-113

[9]

Horie M, 2019, TRANSPLANTATION

[10] Quantitative chest CT for subtyping chronic lung allograft dysfunction and its association with survival [J].

Horie, Miho ;

Salazar, Pascal ;

Saito, Tomohito ;

Binnie, Matthew ;

Brock, Kristy ;

Yasufuku, Kazuhiro ;

Azad, Sassan ;

Keshavjee, Shaf ;

Martinu, Tereza ;

Paul, Narinder .

CLINICAL TRANSPLANTATION, 2018, 32 (05)

← 1 2 3 4 →