Valproate Induced Agitation and Irritability in a Patient With Mania: Case Report

被引:1
|
作者
Erol, Almila [1 ]
Delibas, Hakan [1 ]
Tenekecioglu, Irem [1 ]
Mete, Levent [1 ]
机构
[1] Izmir Ataturk Egitim & Arastirma Hastanesi, Psikiyatri Klin, Izmir, Turkey
来源
KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY | 2010年 / 20卷 / 04期
关键词
Valproate; agitation; irritability; adverse reactions; SODIUM VALPROATE; CHILDHOOD EPILEPSY; DIVALPROEX SODIUM; DISORDER; ACID;
D O I
10.1080/10177833.2010.11790680
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Valproate is a mood-stabilizing anticonvulsant. It is also used in the management of agitation, irritability and impulsive aggressive behavior. Here we report on a 35-year-old male with bipolar disorder who had paradoxical agitation and irritability during valproate therapy. He had bipolar disorder for ten years and he was hospitalized due to his manic episode. At the time of admission he was euphoric but not irritable. He was put on valproate and diazepam. On the fourth day of valproate therapy he became irritable, agitated and hostile. Careful investigation of his previous health records showed that he had had a history of agitation and violence in the past while he was on valproate therapy. His agitation and irritability improved rapidly after discontinuation of valproate. He was discharged from the hospital in remission after two weeks of therapy with lithium. If a patient develops new-onset agitation and irritability or worsening of agitation and irritability after starting valproate for the treatment of agitation and aggression, one needs to consider that this may be a manifestation of an adverse effect of valproate.
引用
收藏
页码:324 / 326
页数:3
相关论文
共 50 条
  • [31] Isotretinoin Induced Psychotic Mania: A Case Report
    Kurhan, Faruk
    Kamis, Gulsum Zuhal
    TURK PSIKIYATRI DERGISI, 2021, 32 (03) : 214 - 218
  • [32] A CASE REPORT OF TRAMADOL-INDUCED MANIA
    Aggarwal, N.
    Gupta, N.
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2016, 50 : 149 - 149
  • [34] Steroid-Induced Mania: A Case Report
    Cassidy, Carol
    Sahay, Shobhna
    McNicholas, Fiona
    IRISH JOURNAL OF PSYCHOLOGICAL MEDICINE, 2012, 29 (03) : 194 - 195
  • [35] MANIA INDUCED BY METOCLOPRAMIDE - CASE-REPORT
    RITCHIE, KS
    PRESKORN, SH
    JOURNAL OF CLINICAL PSYCHIATRY, 1984, 45 (04) : 180 - 181
  • [36] Valproate-Induced Thrombocytopenia: A Case Report
    Surineni, Kamalakar
    Wells, Emilee
    Schrader, Nolan
    Costa, Gilmar
    Ziegler, Maggie
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (07)
  • [37] Paliperidone-induced mania: a case report
    Bal, Nese B.
    Bakir, Meryem G. Teksin
    Caykoylu, Ali
    Ozalp, Elvan
    Kocberber, Cagla
    Yilmazoglu, Bahriye E.
    ARCHIVES OF CLINICAL PSYCHIATRY, 2020, 47 (04) : 119 - 120
  • [38] Antidepressant withdrawal induced mania: A case report
    Priyadarshini, Sarmistha
    Mohapatra, Satyakam
    Verma, Jitendra
    INDIAN JOURNAL OF PSYCHIATRY, 2015, 57 (05) : S119 - S119
  • [39] Mania Possibly Induced by Clozapine: a Case Report
    Oguz, Nihan
    Gulec, Mustafa
    Erol, Almila
    DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES, 2014, 27 (04): : 348 - 351