An Androgen Receptor-positive Carcinoma of the Lacrimal Drainage System Resembling Salivary Duct Carcinoma: Case Report and Review of the Literature

被引：6

作者：

Rahimi, Siavash ^{[1
]}

Lambiase, Alessandro ^{[3
]}

Brennan, Peter A. ^{[2
]}

Abdolrahimzadeh, Solmaz ^{[3
]}

机构：

[1] Queen Alexandra Hosp, Pathol Ctr Histopathol, Southwick Hill Rd, Portsmouth PO6 3LY, Hants, England

[2] Queen Alexandra Hosp, Dept Oral & Maxillofacial Surg, Portsmouth, Hants, England

[3] Univ Roma La Sapienza, Ophthalmol Unit, Azienda Policlin Umberto I, Rome, Italy

来源：

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY | 2016年 / 24卷 / 08期

关键词：

lacrimal; duct carcinoma; androgen receptor; immunohistochemistry; ADENOCARCINOMA; SAC; EFFICACY; TUMORS;

D O I：

10.1097/PAI.0000000000000313

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Carcinomas of the lacrimal drainage apparatus are rare and due to their aggressive behavior, they usually require extensive surgical treatment. We report a unique case of a 60-year-old man presenting with proptosis found to have a mass in the lacrimal drainage system on magnetic resonance imaging. Histology revealed a high-grade carcinoma with morphologic features of salivary gland duct carcinoma. Immunohistochemistry showed an extensive positive staining to androgen receptor. This is the first report of salivary gland-like duct carcinoma of the lacrimal drainage apparatus. Androgen receptor should be included in the immunohistochemical panel for the diagnostic work-up of lacrimal drainage system carcinomas, which resemble salivary gland duct carcinoma. This finding could have important diagnostic and therapeutic implications.

引用

页码：e69 / e71

页数：3

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