Hematopoietic stem cell transplantation for autoimmune diseases: What have we learned?

被引：61

作者：

Burt, Richard K. ^{[1
]}

Testor, Alessandro ^{[1
]}

Craig, Robert ^{[2
]}

Cohen, Bruce ^{[3
]}

Suffit, Robert ^{[3
]}

Barr, Walter ^{[4
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Immunotherapy, Chicago, IL 60611 USA

[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Gastroenterol, Chicago, IL 60611 USA

[3] Northwestern Univ, Feinberg Sch Med, Dept Neurol, Chicago, IL 60611 USA

[4] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Rheumatol, Chicago, IL 60611 USA

来源：

JOURNAL OF AUTOIMMUNITY | 2008年 / 30卷 / 03期

关键词：

hematopoietic stem cell transplantation (HSCT); autologous HSCT; animal models; human trials;

D O I：

10.1016/j.jaut.2007.12.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Numerous individuals and institutions throughout the world have contributed to the development of hematopoietic stem cell transplantation (HSCT) for autoimmune diseases. In this review, we will summarize what we have learned at our own institution (Northwestern University), and how it has guided our therapy. An emphasis will be placed on both the scientific basis for the development of autologous hematopoietic stem cell transplantation and a summary of the data in a variety of human diseases. (C) 2008 Published by Elsevier Ltd.

引用

页码：116 / 120

页数：5

共 57 条

[11] Induction of remission of severe and refractory rheumatoid arthritis by allogeneic mixed chimerism [J].

Burt, RK ;

Oyama, Y ;

Verda, L ;

Quigley, K ;

Brush, M ;

Yaung, K ;

Statkute, L ;

Traynor, A ;

Barr, WG .

ARTHRITIS AND RHEUMATISM, 2004, 50 (08) :2466-2470

[12] Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores [J].

Burt, RK ;

Cohen, BA ;

Russell, E ;

Spero, K ;

Joshi, A ;

Oyama, Y ;

Karpus, WJ ;

Luo, KH ;

Jovanovic, B ;

Traynor, A ;

Karlin, K ;

Stefoski, D ;

Burns, WH .

BLOOD, 2003, 102 (07) :2373-2378

[13] Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis [J].

Burt, RK ;

Padilla, J ;

Begolka, WS ;

Dal Canto, MC ;

Miller, SD .

BLOOD, 1998, 91 (07) :2609-2616

[14] Biomarkers, self-antigens and the immunological homunculus [J].

Cohen, Irun R. .

JOURNAL OF AUTOIMMUNITY, 2007, 29 (04) :246-249

[15] On reversing the persistence of memory: Hematopoietic stem cell transplant for autoimmune disease in the first ten years [J].

Deane, Sean ;

Meyers, Frederick J. ;

Gershwin, M. Eric .

JOURNAL OF AUTOIMMUNITY, 2008, 30 (03) :180-196

[16] Sjogren's syndrome in the NOD mouse model is an interleukin-4 time-dependent, antibody isotype-specific autoimmune disease [J].

Gao, JH ;

Killedar, S ;

Cornelius, JG ;

Nguyen, C ;

Cha, SH ;

Peck, AB .

JOURNAL OF AUTOIMMUNITY, 2006, 26 (02) :90-103

[17] Bone marrow transplantation, refractory autoimmunity and the contributions of Susumu Ikehara [J].

Gershwin, M. Eric .

JOURNAL OF AUTOIMMUNITY, 2008, 30 (03) :105-107

[18] Autologous hematopoietic stem cell transplantation for autoimmune diseases [J].

Gratwohl, A ;

Passweg, J ;

Bocelli-Tyndall, C ;

Fassas, A ;

van Laar, JM ;

Farge, D ;

Andolina, M ;

Arnold, R ;

Carreras, E ;

Finke, J ;

Kötter, I ;

Kozak, T ;

Lisukov, I ;

Löwenberg, B ;

Marmont, A ;

Moore, J ;

Saccardi, R ;

Snowden, JA ;

van den Hoogen, F ;

Wulffraat, NM ;

Zhao, XW ;

Tyndall, A .

BONE MARROW TRANSPLANTATION, 2005, 35 (09) :869-879

[19] In vivo bioimaging using photogenic rats:: Fate of injected bone marrow-derived mesenchymal stromal cells [J].

Hara, Mayumi ;

Murakami, Takashi ;

Kobayashi, Eiji .

JOURNAL OF AUTOIMMUNITY, 2008, 30 (03) :163-171

[20] Innovative BMT methods for intractable diseases [J].

Ikehara, Susumu .

IMMUNOLOGIC RESEARCH, 2007, 38 (1-3) :251-260

← 1 2 3 4 5 6 →