Synthesis of Aromatic Sulfonamides through a Copper-Catalyzed Coupling of Aryldiazonium Tetrafluoroborates, DABCO•(SO2)2, and N-Chloroamines

被引：68

作者：

Zhang, Feng ^{[1
]}

Zheng, Danqing ^{[2
]}

Lai, Lifang ^{[3
,4
]}

Cheng, Jiang ^{[3
,4
]}

Sun, Jiangtao ^{[3
,4
]}

Wu, Jie ^{[2
]}

机构：

[1] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China

[2] Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China

[3] Changzhou Univ, Sch Petrochem Engn, Changzhou 213164, Peoples R China

[4] Changzhou Univ, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China

来源：

ORGANIC LETTERS | 2018年 / 20卷 / 04期

基金：

中国国家自然科学基金;

关键词：

SULFUR-DIOXIDE SURROGATE; MULTICOMPONENT REACTION; ALKYL-HALIDES; ONE-POT; POTASSIUM METABISULFITE; 3-COMPONENT REACTION; SULFONYL CHLORIDES; ARYL SULFONAMIDES; ARYLBORONIC ACIDS; ROOM-TEMPERATURE;

D O I：

10.1021/acs.orglett.8b00093

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A copper-catalyzed aminosulfonylation of aryldiazonium tetrafluoroborates, DABCO center dot(SO2)(2), and N-chloroamines is described. This coupling reaction provides an efficient and simple approach to a wide range of sulfonamides in moderate to good yields under mild conditions. Mechanistic investigation suggests that a radical process and transition-metal catalysis are merged in this tandem reaction.

引用

页码：1167 / 1170

页数：4

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