New anionic crosslinked multi-responsive pullulan hydrogels

被引：30

作者：

Mocanu, Georgeta ^{[1
]}

Mihai, Doina ^{[1
]}

Dulong, Virginie ^{[2
,3
]}

Picton, Luc ^{[2
,3
]}

Le Cerf, Didier ^{[2
,3
]}

机构：

[1] Petru Poni Inst Macromol Chem, Iasi 700487, Romania

[2] Univ Rouen, Lab Polymers Biopolymers Surfaces, CNRS UMR 6270, F-76821 Mont St Aignan, France

[3] Univ Rouen, Lab Polymers Biopolymers Surfaces, FR 3038, F-76821 Mont St Aignan, France

来源：

CARBOHYDRATE POLYMERS | 2012年 / 87卷 / 02期

关键词：

Pullulan; Hydrogels; Thermoassociative; Jeffamine; Crosslinking; N-ISOPROPYLACRYLAMIDE; ANTIOXIDANT ACTIVITY; SWELLING PROPERTIES; TEMPERATURE; CHITOSAN;

D O I：

10.1016/j.carbpol.2011.09.037

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The paper studies the synthesis and characterization of anionic thermoassociative carboxymethylpullulan hydrogels through crosslinking of carboxymethylpullulan with two difunctional Jeffamines: ED-600 and ED-2003; taking into account that the Jeffamines contain polyoxyalkyleneamines (polyethylene oxide, polypropylene oxide) backbone with thermoassociative properties, is expected that the polysaccharide-Jeffamine derivatives also possess amphiphilic and thermosensitive characteristics. The hydrogels were characterized through FTIR spectra, swelling behavior in various media, at various pH or temperatures, retention of hydrophobic molecules, to appreciate their polyelectrolyte and thermoassociative properties. The interaction with biomolecules as proteins: lysozyme and BSA and as antioxidants: lutein was studied to estimate some potential application domains of these newly synthesized hydrogels. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1440 / 1446

页数：7

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