Low regional cerebral blood flow in burning mouth syndrome patients with depression

被引：13

作者：

Liu, B-L ^{[1
]}

Yao, H. ^{[1
]}

Zheng, X-J ^{[2
]}

Du, G-H ^{[1
]}

Shen, X-M ^{[1
]}

Zhou, Y-M ^{[1
]}

Tang, G-Y ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Med, Peoples Hosp 9, Shanghai Key Lab Stomatol,Dept Oral Mucosal Dis, Shanghai 200011, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Nucl Med, Shanghai 200011, Peoples R China

来源：

ORAL DISEASES | 2015年 / 21卷 / 05期

基金：

美国国家科学基金会;

关键词：

burning mouth syndrome; depression; emotional disorder; cerebral blood flow; SPECT; CT; SYSTEMIC-LUPUS-ERYTHEMATOSUS; CHRONIC PAIN; FMRI;

D O I：

10.1111/odi.12322

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

ObjectivesThe main aims of this study were to (i) investigate the emotional disorder status of patients with burning mouth syndrome (BMS) and (ii) detect regional cerebral blood flow in BMS patients with the application of combined single-photon emission computed tomography and computed tomography (SPECT/CT). Subjects and MethodsThe degree of pain was measured using the visual analysis scale, and emotional disorder with the self-rating anxiety scale, self-rating depression scale, and Hamilton depression rating scale in 29 patients with BMS and 10 healthy controls. SPECT/CT was performed in 29 patients with BMS and 10 healthy controls, and statistical parametric mapping method was used for between-group analyses. ResultsThe incidence rate of depression in patients with BMS was 31.0%. Compared to the control group, patients with BMS displayed significantly different depression and anxiety scales (P<0.05). Significantly lower regional cerebral blood flow in the left parietal and left temporal lobes was recorded for BMS patients with depression (P<0.05). ConclusionsPatients with BMS experience more depression and anxious emotion. Moreover, depression in patients with BMS may be associated with lower regional cerebral blood flow in the left temporal and left parietal lobes.

引用

页码：602 / 607

页数：6

共 18 条

[1] Cerebral activation during thermal stimulation of patients who have burning mouth disorder: An fMRI study [J].

Albuquerque, Romulo J. C. ;

de Leeuw, Reny ;

Carlson, Charles R. ;

Okeson, Jeffrey P. ;

Miller, Craig S. ;

Andersen, Anders H. .

PAIN, 2006, 122 (03) :223-234

[2] PERSONALITY-CHARACTERISTICS OF PATIENTS WITH RESISTANT BURNING MOUTH SYNDROME [J].

BERGDAHL, J ;

ANNEROTH, G ;

PERRIS, H .

ACTA ODONTOLOGICA SCANDINAVICA, 1995, 53 (01) :7-11

[3]

Bergdahl M, 1999, J ORAL PATHOL MED, V28, P350

[4] Chronic pain and psychopathology: Research findings and theoretical considerations [J].

Dersh, J ;

Polatin, PB ;

Gatchel, RJ .

PSYCHOSOMATIC MEDICINE, 2002, 64 (05) :773-786

[5] Cerebral Blood Flow in Depressed Patients with Systemic Lupus Erythematosus [J].

Giovacchini, Giampiero ;

Mosca, Marta ;

Manca, Gianpiero ;

Della Porta, Mauro ;

Neri, Claudia ;

Bombardieri, Stefano ;

Ciarmiello, Andrea ;

Strauss, H. William ;

Mariani, Giuliano ;

Volterrani, Duccio .

JOURNAL OF RHEUMATOLOGY, 2010, 37 (09) :1844-1851

[6] Burning mouth syndrome [J].

Gurvits, Grigoriy E. ;

Tan, Amy .

WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (05) :665-672

[7]

Headache Classification Subcommittee of the International Headache Society, 2004, CEPHALALGIA S1, V24, P133

[8] Pathophysiology of primary burning mouth syndrome [J].

Jaaskelainen, Satu K. .

CLINICAL NEUROPHYSIOLOGY, 2012, 123 (01) :71-77

[9] Role of the dopaminergic system in chronic pain -: a fluorodopa-PET study [J].

Jääskeläinen, SK ;

Rinne, JO ;

Forssell, H ;

Tenovuo, O ;

Kaasinen, V ;

Sonninen, P ;

Bergman, J .

PAIN, 2001, 90 (03) :257-260

[10] Burning mouth syndrome (BMS) and the concept of alexithymia - A preliminary study [J].

Jerlang, BB .

JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1997, 26 (06) :249-253

← 1 2 →