Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation

被引：9
作者：
Lazaro-Navarro, Juan [1 ,2 ]
Pimentel-Gutierrez, Helia Judith [1 ,2 ]
Gauert, Anton [1 ,2 ]
Hagemann, Anja I. H. [1 ]
Eisenschmid, Jassi [3 ,4 ]
Goekbuget, Nicola [2 ,4 ]
Vick, Binje [2 ,5 ]
Jeremias, Irmela [2 ,5 ]
Seyfried, Felix [6 ]
Meyer, Luder Hinrich [6 ]
Debatin, Klaus-Michael [6 ]
Richer, Kathrin [7 ]
Bultman, Miriam [7 ]
Neumann, Martin [2 ,7 ]
Hanzelmann, Sonja [2 ]
Serve, Hubert [2 ,3 ,4 ]
Astrahantseff, Kathy [1 ]
Rieger, Michael A. [2 ,3 ,4 ]
Eckert, Cornelia [1 ,2 ]
Baldus, Claudia D. [2 ,7 ]
Bastian, Lorenz [2 ,7 ]
机构：
[1] Charit Univ med Berlin, Dept Pediat Oncol Hematol, Berlin, Germany
[2] German Canc Res Ctr, German Canc Consortium DKTK, Heidelberg, Germany
[3] Frankfurt Canc Inst, Frankfurt, Germany
[4] Goethe Univ Hosp Frankfurt, Dept Med Hematol Oncol, Frankfurt, Germany
[5] Helmholtz Ctr Munich German Ctr Environm Hlth HMG, Dept Apoptosis Hematopoiet Stem Cells, Munich, Germany
[6] Univ Ulm, Dept Pediat & Adolescent Med, Med Ctr, Ulm, Germany
[7] Univ Med Ctr Schleswig Holstein, Med Dept 2, Hematol Oncol, Campus Kiel, Kiel, Germany
来源：
BLOOD ADVANCES | 2021年 / 5卷 / 24期
关键词：
BCL-2; DEPENDENCE; APOPTOSIS; CK2; ACTIVATION; GENOMICS;
D O I：
10.1182/bloodadvances.2021004513
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：5501 / 5506
页数：6
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