SARS-CoV-2 infection in kidney transplant recipients: Early report of five cases

被引:12
作者
Silva, Filipa [1 ]
Cipriano, Ana [2 ]
Cruz, Hugo [3 ]
Tavares, Joana [1 ]
Fragoso, Joana [2 ]
Malheiro, Jorge [1 ]
Almeida, Manuela [1 ]
Martins, La Salete [1 ]
Abreu, Miguel [2 ]
Pedroso, Sofia [1 ]
Dias, Leonidio [1 ]
Henriques, Antonio Castro [1 ]
机构
[1] Ctr Hosp & Univ Porto, Nephrol & Kidney Transplantat Dept, Largo Prof Abel Salazar 1, P-4099001 Porto, Portugal
[2] Ctr Hosp & Univ Porto, Dept Infect Dis, Porto, Portugal
[3] Ctr Hosp & Univ Porto, Dept Microbiol, Porto, Portugal
关键词
COVID-19; infection; kidney transplantation; MYCOPHENOLATE-MOFETIL; COVID-19; MORTALITY; SEPSIS;
D O I
10.1111/tid.13394
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
From December 2019 to March 2020, China was the epicenter of the SARS-CoV-2 infection pandemic, but from that moment on, Europe surpassed China in the number of new cases and deaths related to this novel viral respiratory infection. The emergence of this world pandemic is particularly important for solid organ transplant recipients, who might have an increased risk of mortality, not only due to their chronic immunosuppression status, but also to the cardiovascular risk that correlates with several years of chronic kidney disease. To the extent that there is still a lack of knowledge about the clinical characteristics, evolution, and prognosis of SARS-CoV-2 infection in kidney transplant recipients, we will report the first 5 cases diagnosed and followed in our transplant unit, as well as share the therapeutic strategies adopted.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] Outcomes following SARS-CoV-2 infection in liver transplant recipients: an international registry study
    Webb, Gwilym J.
    Marjot, Thomas
    Cook, Jonathan A.
    Aloman, Costica
    Armstrong, Matthew J.
    Brenner, Erica J.
    Catana, Maria-Andreea
    Cargill, Tamsin
    Dhanasekaran, Renumathy
    Garcia-Juarez, Ignacio
    Hagstrom, Hannes
    Kennedy, James M.
    Marshall, Aileen
    Masson, Steven
    Mercer, Carolyn J.
    Perumalswami, Ponni, V
    Ruiz, Isaac
    Thaker, Sarang
    Ufere, Nneka N.
    Barnes, Eleanor
    Barritt, Alfred S.
    Moon, Andrew M.
    LANCET GASTROENTEROLOGY & HEPATOLOGY, 2020, 5 (11): : 1008 - 1016
  • [42] Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients
    Charmetant, Xavier
    Espi, Maxime
    Benotmane, Ilies
    Barateau, Veronique
    Heibel, Francoise
    Buron, Fanny
    Gautier-Vargas, Gabriela
    Delafosse, Marion
    Perrin, Peggy
    Koenig, Alice
    Cognard, Noelle
    Levi, Charlene
    Gallais, Floriane
    Maniere, Louis
    Rossolillo, Paola
    Soulier, Eric
    Pierre, Florian
    Ovize, Anne
    Morelon, Emmanuel
    Defrance, Thierry
    Fafi-Kremer, Samira
    Caillard, Sophie
    Thaunat, Olivier
    SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (636)
  • [43] Protecting kidney transplant recipients against SARS-CoV-2 infection: A third dose of vaccine is necessary now
    Villanego, Florentino
    Cazorla, Juan Manuel
    Vigara, Luis Alberto
    Garcia, Teresa
    Trujillo, Teresa
    Montiel, Natalia
    Rodriquez-Iglesias, Manuel
    Mazuecos, Auxiliadora
    AMERICAN JOURNAL OF TRANSPLANTATION, 2022, 22 (04) : 1275 - 1276
  • [44] The Impact of SARS-CoV-2 Infection, and Application of Immunosuppressive Agents in Kidney Transplant Recipients Suffering from COVID-19
    Tseng, Horng-Ta
    Wu, Xiang-Chi
    Huang, Chun-Yao
    Shih, Chun-Ming
    Lin, Yi-Wen
    Lin, Feng-Yen
    PHARMACEUTICALS, 2021, 14 (10)
  • [45] Is transplantation per se a risk factor for worse outcome of SARS-CoV-2 infection in kidney transplant recipients?
    van Delden, Christian
    TRANSPLANT INTERNATIONAL, 2021, 34 (05) : 775 - 777
  • [46] Influence of immunosuppression on seroconversion against SARS-CoV-2 in two kidney transplant recipients
    Wang, Aileen X.
    Cardona, Orlando Quintero
    Ho, Dora Y.
    Busque, Stephan
    Lenihan, Colin R.
    TRANSPLANT INFECTIOUS DISEASE, 2021, 23 (01)
  • [47] Immunologic response of mRNA SARS-CoV-2 vaccination in adolescent kidney transplant recipients
    Clarkson Crane
    Erin Phebus
    Elizabeth Ingulli
    Pediatric Nephrology, 2022, 37 : 449 - 453
  • [48] Optimizing SARS-CoV-2 vaccine responses in kidney transplant recipients: an urgent need
    Cheng, Yi-Ling
    Chang, Shen-Shin
    Chao, Chiao-Hsuan
    Chen, Po-Ta
    Lin, Ya-Lan
    Syu, Guan-Da
    Lee, Nan-Yao
    Chen, Po-Lin
    Ko, Wen-Chien
    Ho, Tzong-Shiann
    MICROBIOLOGY SPECTRUM, 2024, 12 (06):
  • [49] Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination in Kidney Transplant Recipients
    Mazuecos, Auxiliadora
    Villanego, Florentino
    Zarraga, Sofia
    Lopez, Veronica
    Oppenheimer, Federico
    Llinas-Mallol, Laura
    Hernandez, Ana M.
    Rivas, Alba
    Ruiz-Fuentes, Maria C.
    Toapanta, Nestor G.
    Jimenez, Carlos
    Cabello, Sheila
    Beneyto, Isabel
    Aladren, Maria J.
    Rodriguez-Benot, Alberto
    Canal, Cristina
    Molina, Maria
    Perez-Flores, Isabel
    Saura, Isabel M.
    Gavela, Eva
    Franco, Antonio
    Lorenzo, Inmaculada
    Galeano, Cristina
    Tabernero, Guadalupe
    Perez-Tamajon, Lourdes
    Martin-Moreno, Paloma L.
    Fernandez-Giron, Fernando
    Siverio, Orlando
    Labrador, Pedro J.
    De Arriba, Gabriel
    Simal, Fernando
    Cruzado, Leonidas
    Moina, Inigo
    Alcalde, Guillermo
    Sanchez-Alvarez, Emilio
    Pascual, Julio
    Crespo, Marta
    TRANSPLANTATION, 2022, 106 (07) : 1430 - 1439
  • [50] Immunologic response to SARS-CoV-2 mRNA vaccination in pediatric kidney transplant recipients
    Kermond, Rachael F.
    Ozimek-Kulik, Justyna E.
    Kim, Siah
    Alexander, Stephen, I
    Hahn, Deirdre
    Kesson, Alison
    Wood, Nicholas
    McCarthy, Hugh J.
    Durkan, Anne M.
    PEDIATRIC NEPHROLOGY, 2023, 38 (03) : 859 - 866