Dysfunctional HDAC8 Impacts Genomic Integrity and Is a Novel Therapeutic Target in Multiple Myeloma

被引：0

作者：

Chyra, Zuzana ^{[1
,2
,3
,4
]}

Talluri, Srikanth ^{[5
,6
]}

Prabhala, Rao ^{[5
,6
]}

Samur, Mehmet K. ^{[7
,8
]}

Aktas-Samur, Anil ^{[9
,10
]}

Xu, Yan ^{[10
,11
]}

Beeler, Aaron B. ^{[12
,13
]}

Hajek, Roman ^{[14
,15
,16
]}

Fulciniti, Mariateresa ^{[10
]}

Shammas, Masood A. ^{[6
,17
]}

Munshi, Nikhil C. ^{[18
,19
,20
]}

机构：

[1] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, LeBow Inst Myeloma Therapeut, Boston, MA USA

[2] Harvard Med Sch, Jerome Lipper Multiple Myeloma Ctr, Dept Med Oncol, DanaFarber Canc Inst, Boston, MA USA

[3] Univ Hosp Ostrava, Dept Hemato Oncol, Ostrava, Czech Republic

[4] Univ Ostrava, Dept Internal Studies, Ostrava, Czech Republic

[5] Dana Farber Canc Inst, Boston, MA USA

[6] VA Boston Healthcare Syst, Boston, MA USA

[7] Dana Farber Canc Inst, Dept Data Sci, Boston, MA USA

[8] Harvard Med Sch, DanaFarber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA

[9] Dana Farber Canc Inst, Dept Data Sci, Boston, MA USA

[10] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA

[11] Chinese Acad Med Sci Peking Union Med Coll, Inst Hematol Blood Dis Hosp, Tianjin, Peoples R China

[12] Boston Univ, Dept Chem, Boston, MA USA

[13] Boston Univ, Ctr Mol Discovery, Boston, MA USA

[14] Czech Myeloma Grp, Brno, Czech Republic

[15] Univ Hosp Ostrava, Dept Haematooncol, Ostrava, Czech Republic

[16] Univ Ostrava, Dept Clin Studies, Fac Med, Ostrava, Czech Republic

[17] Harvard Med Sch, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA

[18] Harvard Med Sch, DanaFarber Canc Inst, Boston, MA USA

[19] Boston VA Healthcare Syst, West Roxbury, MA USA

[20] Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA

来源：

关键词：

D O I：

10.1182/blood-2021-153382

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1610

引用

页数：4