Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots

被引:26
作者
Markovic, Zoran M. [1 ]
Kovacova, Maria [2 ,3 ]
Jeremic, Sanja R. [4 ]
Nagy, Stefan [5 ]
Milivojevic, Dusan D. [1 ]
Kubat, Pavel [6 ]
Kleinova, Angela [2 ]
Budimir, Milica D. [1 ]
Mojsin, Marija M. [4 ]
Stevanovic, Milena J. [4 ,7 ,8 ]
Annusova, Adriana [9 ,10 ]
Spitalsky, Zdeno [2 ]
Markovic, Biljana M. Todorovic [1 ]
机构
[1] Univ Belgrade, Vinca Inst Nucl Sci, Natl Inst Republ Serbia, Belgrade 11000, Serbia
[2] Slovak Acad Sci, Polymer Inst, Dubravska Cesta 9, Bratislava 84541, Slovakia
[3] Masaryk Univ, Fac Sci, Dept Phys Elect, Kotlarska 2, Brno 61137, Czech Republic
[4] Univ Belgrade, Inst Mol Genet & Genet Engn, Vojvode Stepe 444a, Belgrade 11042, Serbia
[5] Slovak Acad Sci, Inst Mat & Machine Mech, Dubravska Cesta 9-6319, Bratislava 84513, Slovakia
[6] Acad Sci Czech Republ, J Heyrovsky Inst Phys Chem, Dolejskova 3, Prague 18223, Czech Republic
[7] Univ Belgrade, Fac Biol, Studentski Trg 16, Belgrade 11000, Serbia
[8] Serbian Acad Arts & Sci, Knez Mihailova 35, Belgrade 11000, Serbia
[9] Slovak Acad Sci, Inst Phys, Dept Multilayers & Nanostruct, Dubravska Cesta 9, Bratislava 84541, Slovakia
[10] Slovak Acad Sci, Ctr Adv Mat Applicat, Dubravska Cesta 9, Bratislava 84511, Slovakia
关键词
riboflavin; carbon polymerized dots; polymer composites; antibacterial surfaces; GRAPHENE QUANTUM DOTS; ULTRAVIOLET-LIGHT; PHOTOLUMINESCENCE MECHANISM; MOLECULAR-OXYGEN; MOBILE PHONES; INACTIVATION; EMISSION; PHOTOCHEMISTRY; FLUORESCENT; BACTERIAL;
D O I
10.3390/nano12224070
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate Escherichia coli in 30 min, whereas the same effect toward Staphylococcus aureus was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry.
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页数:17
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