Exploring the Potential of Natural Product-Based Nanomedicine for Maintaining Oral Health

被引:18
作者
Kumar, Rajeev [1 ]
Mirza, Mohd A. [2 ]
Naseef, Punnoth Poonkuzhi [3 ]
Kuruniyan, Mohamed Saheer [4 ]
Zakir, Foziyah [1 ]
Aggarwal, Geeta [1 ]
机构
[1] Delhi Pharmaceut Sci & Res Univ, Sch Pharmaceut Sci, Dept Pharmaceut, Sect 3,MB Rd, New Delhi 110017, India
[2] Jamia Hamdard, Dept Pharmaceut, Sch Pharmaceut Educ & Res, New Delhi 110062, India
[3] Moulana Coll Pharm, Dept Pharmaceut, Perinthalmanna 679321, India
[4] King Khalid Univ, Coll Appl Med Sci, Dept Dent Technol, Abha 61421, Saudi Arabia
来源
MOLECULES | 2022年 / 27卷 / 05期
关键词
dental diseases; essential oils; herb; natural products; nanotechnology; regulations; SOLID LIPID NANOPARTICLES; SQUAMOUS-CELL CARCINOMA; ESSENTIAL OIL; IN-VITRO; ENHANCED BIOAVAILABILITY; DELIVERY-SYSTEM; CHLORHEXIDINE; CURCUMIN; VIVO; NANOTECHNOLOGY;
D O I
10.3390/molecules27051725
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Oral diseases pose a major threat to public health across the globe. Diseases such as dental caries, periodontitis, gingivitis, halitosis, and oral cancer affect people of all age groups. Moreover, unhealthy diet practices and the presence of comorbidities aggravate the problem even further. Traditional practices such as the use of miswak for oral hygiene and cloves for toothache have been used for a long time. The present review exhaustively explains the potential of natural products obtained from different sources for the prevention and treatment of dental diseases. Additionally, natural medicine has shown activity in preventing bacterial biofilm resistance and can be one of the major forerunners in the treatment of oral infections. However, in spite of the enormous potential, it is a less explored area due to many setbacks, such as unfavorable physicochemical and pharmacokinetic properties. Nanotechnology has led to many advances in the dental industry, with various applications ranging from maintenance to restoration. However, can nanotechnology help in enhancing the safety and efficacy of natural products? The present review discusses these issues in detail.
引用
收藏
页数:21
相关论文
共 122 条
[31]   Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin [J].
Eid, Eltayeb E. M. ;
Abdul, Ahmad Bustamam ;
Suliman, Fakhr Eldin O. ;
Sukari, Mohd A. ;
Rasedee, A. ;
Fatah, Safa S. .
CARBOHYDRATE POLYMERS, 2011, 83 (04) :1707-1714
[33]   Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance [J].
El-Samaligy, Mohamed S. ;
Afifi, Nagia N. ;
Mahmoud, Enas A. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2006, 319 (1-2) :121-129
[34]   Lawsonia inermis essential oil: extraction optimization by RSM, antioxidant activity, lipid peroxydation and antiproliferative effects [J].
Elaguel, Asma ;
Kallel, Imen ;
Gargouri, Bochra ;
Ben Amor, Ichrak ;
Hadrich, Bilel ;
Ben Messaoud, Ezeddine ;
Gdoura, Radhouane ;
Lassoued, Saloua ;
Gargouri, Ahmed .
LIPIDS IN HEALTH AND DISEASE, 2019, 18 (01)
[35]  
Fekrazad Reza, 2017, Braz. Dent. J., V28, P72, DOI 10.1590/0103-6440201700737
[36]  
Ferreira de Oliveira M.A.F., 2018, COCHRANE DB SYST REV, V2, DOI [10.1002/14651858.CD003454.pub2, DOI 10.1002/14651858.CD003454.PUB2]
[37]   PHYTOTHERAPY IN THE MODERN WORLD [J].
Ferreira, Vitor F. ;
Pinto, Angelo C. .
QUIMICA NOVA, 2010, 33 (09) :1829-1829
[38]   Laminated chitosan-based composite sponges for transmucosal delivery of novel protamine-decorated tripterine phytosomes: Ex-vivo mucopenetration and in-vivo pharmacokinetic assessments [J].
Freag, May S. ;
Saleh, Wedad M. ;
Abdallah, Ossama Y. .
CARBOHYDRATE POLYMERS, 2018, 188 :108-120
[39]   Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles, in-Vitro, Ex-Vivo and in-Vivo Characteristics [J].
Ghaffari, Solmaz ;
Alihosseini, Faezeh ;
Sorkhabadi, Seyed Mahdi Rezayat ;
Bidgoli, Sepideh Arbabi ;
Mousavi, Seyyedeh Elaheh ;
Haghighat, Setareh ;
Nasab, Ahoo Afshar ;
Kianvash, Nooshin .
ADVANCED PHARMACEUTICAL BULLETIN, 2018, 8 (03) :395-400
[40]   Antimicrobial activity of garlic, tea tree oil, and chlorhexidine against oral microorganisms [J].
Groppo, FC ;
Ramacciato, JC ;
Simoes, RP ;
Flório, FM ;
Sartoratto, A .
INTERNATIONAL DENTAL JOURNAL, 2002, 52 (06) :433-437